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Thalidomide-5-O-CH2-COOH - CAS 2467425-53-0

Inquiry

Thalidomide-5-O-CH2-COOH is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide and NH-PEG3-NH-Boc. It acts as a ligand for Cereblon to recruit CRBN protein.

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Molecular Formula
C15H12N2O7
Molecular Weight
332.26

Thalidomide-5-O-CH2-COOH

    • Specification
      • Synonyms
        Acetic acid, 2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]oxy]-; 2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]oxy}acetic acid
    • Properties
      • InChI Key
        DTZXDGPVNFRIOU-UHFFFAOYSA-N
        InChI
        InChI=1S/C15H12N2O7/c18-11-4-3-10(13(21)16-11)17-14(22)8-2-1-7(24-6-12(19)20)5-9(8)15(17)23/h1-2,5,10H,3-4,6H2,(H,19,20)(H,16,18,21)
        Canonical SMILES
        C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C=C(C=C3)OCC(=O)O
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