Amino-PEG4-propionic acid

 CAS No.: 663921-15-1  Cat No.: BP-500124  Purity: > 98.0 % 4.5  

Amino-PEG4-propionic acid is a medium-length PEG linker intermediate designed to improve antibody solubility and conjugation stability in ADCs. It enhances drug loading efficiency and supports controlled payload release for targeted therapies.

Amino-PEG4-propionic acid

Structure of 663921-15-1

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Category
PROTAC Linker
Molecular Formula
C11H23NO6
Molecular Weight
265.30
Appearance
Solid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
> 98.0 %
Solubility
10 mm in DMSO
Appearance
Solid
Storage
-20 °C
Shipping
Room temperature, or blue ice upon request.
IUPACName
3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid
Synonyms
1-Amino-3,6,9,12-tetraoxapentadecan-15-oic acid; Amino-PEG4-acid; (PEO)4-amino-propionic acid
Boiling Point
409.6±40.0 °C at 760 mmHg
Density
1.1±0.1 g/cm3
InChI Key
DKUZHSDZSMQOGQ-UHFFFAOYSA-N
InChI
InChI=1S/C11H23NO6/c12-2-4-16-6-8-18-10-9-17-7-5-15-3-1-11(13)14/h1-10,12H2,(H,13,14)
Canonical SMILES
C(COCCOCCOCCOCCN)C(=O)O

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It is commonly abbreviated as: C1V1 = C2V2

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Historical Records: Azido-PEG10-alcohol | Tetraethylene glycol monotosylate | Boc-PEG4-acid | Fmoc-N-amido-PEG12-acetic acid | MZ2 | Amino-PEG2-t-butyl ester | Boc-5-aminovaleric acid | t-Boc-aminooxyacetic Acid N-Hydroxysuccinimide Ester | Propargyl-PEG2-amine | 1-Boc-piperazine | Amino-PEG4-propionic acid

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