Thalidomide-NH-C5-NH2 hydrochloride - CAS 2375194-03-7

Thalidomide-NH-C5-NH2 hydrochloride is a synthetic E3 ligand-linker conjugate containing a cereblon ligand based on Thalidomide and a C5 alkyl linker with terminal amine, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand.

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Molecular Formula
C₁₈H₂₃ClN₄O₄
Molecular Weight
394.85

Thalidomide-NH-C5-NH2 hydrochloride

    • Specification
      • Storage
        -20°C, sealed storage, away from moisture and light; In solvent, -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        4-(5-aminopentylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride
        Synonyms
        Pomalidomide - linker 4
    • Properties
      • InChI Key
        LPILBSGWFJLZPU-UHFFFAOYSA-N
        InChI
        1S/C18H22N4O4.ClH/c19-9-2-1-3-10-20-12-6-4-5-11-15(12)18(26)22(17(11)25)13-7-8-14(23)21-16(13)24;/h4-6,13,20H,1-3,7-10,19H2,(H,21,23,24);1H
        Canonical SMILES
        NCCCCCNC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O.Cl
        Pub Chem ID
        131999658
Bio Calculators
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Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g
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