Thalidomide-O-C4-NH2 hydrochloride

 CAS No.: 2376990-29-1  Cat No.: BP-100122  Purity: ≥95% by HPLC  HPLC  HNMR  MS 4.5  

Thalidomide-O-C4-NH2 hydrochloride is a synthetic E3 ligand-linker conjugate containing a cereblon ligand based on Thalidomide and a C4 alkyl linker with terminal amine, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand.

Thalidomide-O-C4-NH2 hydrochloride

Structure of 2376990-29-1

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Category
E3 Ligase Ligand-Linker Conjugate
Molecular Formula
C₁₇H₂₀ClN₃O₅
Molecular Weight
381.81

* For research and manufacturing use only. Not for human or clinical use.

SizePriceStockQuantity
100 mg $3980 In stock

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Purity
≥95% by HPLC
Storage
Store at -20°C
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
4-(4-aminobutoxy)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride
Synonyms
Thalidomide-linker 9
InChI Key
VRXZGWPQXJYEPH-UHFFFAOYSA-N
InChI
InChI=1S/C17H19N3O5.ClH/c18-8-1-2-9-25-12-5-3-4-10-14(12)17(24)20(16(10)23)11-6-7-13(21)19-15(11)22;/h3-5,11H,1-2,6-9,18H2,(H,19,21,22);1H
Canonical SMILES
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCCCCN.Cl

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: PROTAC ER Degrader-3 | AZD-9291 | ATRA-hydroxyimino | t-Boc-N-amido-PEG2-amine | Thalidomide-NH-PEG1-NH2 hydrochloride | ABBV-744 | Pomalidomide-PEG2-NH2 dihydrochloride | (S,R,S)-AHPC-PEG2-NH2 hydrochloride | cIAP1 Ligand-Linker Conjugates 6 hydrochloride | (S,R,S)-AHPC-PEG1-azide | Thalidomide-O-C4-NH2 hydrochloride

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