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mPEG3-amine - CAS 74654-07-2

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m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

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Molecular Formula
C7H17NO3
Molecular Weight
163.21

mPEG3-amine

    • Specification
      • Purity
        ≥95%
        Solubility
        Soluble in DCM, DMF, DMSO, Water
        Appearance
        Pale Yellow or Colorless Oily Matter
        Shelf Life
        0-4℃ for short term (days to weeks), or -20℃ for long term (months).
        Storage
        Store at 2-8°C
        Shipping
        Room temperature, or blue ice upon request.
        IUPAC Name
        2-[2-(2-methoxyethoxy)ethoxy]ethanamine
        Synonyms
        m-PEG3-amine; 2-[2-(2-Methoxyethoxy)ethoxy]ethylamine; mPEG3-NH2; 2-(2-(2-methoxyethoxy)ethoxy)ethan-1-amine; Ethanamine, 2-[2-(2-methoxyethoxy)ethoxy]-; Methyl-PEG3-amine; 3,6,9-Trioxadecane-1-amine; 3,6,9-Trioxa-1-aminodecane
    • Properties
      • Boiling Point
        223.9±20.0°C at 760 mmHg
        Density
        0.978±0.06 g/cm3 (Predicted)
        InChI Key
        OKUWOEKJQRUMBW-UHFFFAOYSA-N
        InChI
        InChI=1S/C7H17NO3/c1-9-4-5-11-7-6-10-3-2-8/h2-8H2,1H3
        Canonical SMILES
        COCCOCCOCCN
        Biological Activity
        m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
    • Preparing Stock Solutions
      • ConcentrationVolumeMass1 mg5 mg10 mg
        1 mM6.1271 mL30.6354 mL61.2708 mL
        5 mM1.2254 mL6.1271 mL12.2542 mL
        10 mM0.6127 mL3.0635 mL6.1271 mL
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L

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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