BrCH2CONH-PEG2-NHS ester

 CAS No.: 1353011-78-5  Cat No.: BP-500601  Purity: ≥95% 4.5  

BrCH2CONH-PEG2-NHS ester is a PEG linker containing a bromide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

BrCH2CONH-PEG2-NHS ester

Structure of 1353011-78-5

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PROTAC Linker
Molecular Formula
C13H19BrN2O7
Molecular Weight
395.21

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DMSO
Storage
Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[(2-bromoacetyl)amino]ethoxy]ethoxy]propanoate
Synonyms
Bromoacetamido-PEG2-NHS ester; Bromoacetamido-PEG2-C2-NHS ester; 2,5-dioxopyrrolidin-1-yl 3-(2-(2-(2-bromoacetamido)ethoxy)ethoxy)propanoate; 2-Bromo-N-[2-(2-{3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethoxy)ethyl]acetamide; Acetamide, 2-bromo-N-[2-[2-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]ethoxy]ethyl]-
Density
1.5±0.1 g/cm3
InChI Key
HDIXVXMKIWXBFA-UHFFFAOYSA-N
InChI
InChI=1S/C13H19BrN2O7/c14-9-10(17)15-4-6-22-8-7-21-5-3-13(20)23-16-11(18)1-2-12(16)19/h1-9H2,(H,15,17)
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)CCOCCOCCNC(=O)CBr

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It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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