mPEG3-amine

 CAS No.: 74654-07-2  Cat No.: BP-500126  Purity: ≥95%  HNMR  MS 4.5  

mPEG3-amine is a short-chain, amine-functionalized PEG linker offering compact size for ADC applications. Enhances solubility and stability of antibody-drug complexes while minimizing steric hindrance.

mPEG3-amine

Structure of 74654-07-2

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Category
PROTAC Linker
Molecular Formula
C7H17NO3
Molecular Weight
163.21
Appearance
Pale Yellow or Colorless Oily Matter

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DCM, DMF, DMSO, Water
Appearance
Pale Yellow or Colorless Oily Matter
ShelfLife
0-4°C for short term (days to weeks), or -20°C for long term (months).
Storage
Store at 2-8°C
Shipping
Room temperature, or blue ice upon request.
IUPACName
2-[2-(2-methoxyethoxy)ethoxy]ethanamine
Synonyms
m-PEG3-amine; 2-[2-(2-Methoxyethoxy)ethoxy]ethylamine; mPEG3-NH2; 2-(2-(2-methoxyethoxy)ethoxy)ethan-1-amine; Ethanamine, 2-[2-(2-methoxyethoxy)ethoxy]-; Methyl-PEG3-amine; 3,6,9-Trioxadecane-1-amine; 3,6,9-Trioxa-1-aminodecane
Boiling Point
223.9±20.0°C at 760 mmHg
Density
0.978±0.06 g/cm3 (Predicted)
InChI Key
OKUWOEKJQRUMBW-UHFFFAOYSA-N
InChI
InChI=1S/C7H17NO3/c1-9-4-5-11-7-6-10-3-2-8/h2-8H2,1H3
Canonical SMILES
COCCOCCOCCN
Biological Activity
m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
ConcentrationVolumeMass1 mg5 mg10 mg
1 mM6.1271 mL30.6354 mL61.2708 mL
5 mM1.2254 mL6.1271 mL12.2542 mL
10 mM0.6127 mL3.0635 mL6.1271 mL

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Historical Records: SPDPH | HO-PEG24-CH2COOH | m-PEG8-ethoxycarbonyl-NHS ester | Fmoc-NH-PEG11-CH2CH2COOH | 2-Amino-1,3-bis(carboxylethoxy)propane | FmocNH-PEG3-CH2CH2NH2 HCl | mPEG3-amine

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