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Tbdms-PEG4-alcohol - CAS 134179-40-1

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Tbdms-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It contains a TBDMS alcohol protecting group and a terminal hydroxyl group. TBDMS can be removed in the presence of acetyl chloride. The hydroxyl group can be derived into other compounds by other reactions. The hydrophilic PEG linker can increase the solubility of compounds in aqueous media.

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Molecular Formula
C14H32O5Si
Molecular Weight
308.49

Tbdms-PEG4-alcohol

    • Specification
      • Purity
        ≥95%
        Solubility
        Soluble in DMSO
        Appearance
        Colorless Oily Matter
        Storage
        Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        2-[2-[2-[2-[tert-butyl(dimethyl)silyl]oxyethoxy]ethoxy]ethoxy]ethanol
        Synonyms
        TBDMS-PEG5; 13,13,14,14-Tetramethyl-3,6,9,12-tetraoxa-13-sila-1-pentadecanol; 2,2,3,3-Tetramethyl-4,7,10,13-tetraoxa-3-silapentadecan-15-ol; 2-[2-(2-TBDMSO-ethoxy)ethoxy]ethoxy]ethanol; TBDMS-PEG4-OH
    • Properties
      • Boiling Point
        349.6±27.0 °C at 760 mmHg
        Density
        1.0±0.1 g/cm3
        InChI Key
        KZFZMISGZPOLJM-UHFFFAOYSA-N
        InChI
        InChI=1S/C14H32O5Si/c1-14(2,3)20(4,5)19-13-12-18-11-10-17-9-8-16-7-6-15/h15H,6-13H2,1-5H3
        Canonical SMILES
        CC(C)(C)[Si](C)(C)OCCOCCOCCOCCO
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It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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