Thalidomide, propargyl - CAS 2098487-39-7

Thalidomide, propargyl is a cereblon-recruiting ligand consisting of an E3 ubiquitin ligase thalidomide conjugated to an alkyne linker ready for a target protein ligand. It has been used in PROTAC technology for target protein degradation.

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Molecular Formula
C16H12N2O5
Molecular Weight
312.28

Thalidomide, propargyl

    • Specification
      • Purity
        ≥98%
        Synonyms
        2-(2,6-Dioxo-3-piperidinyl)-4-(2-propyn-1-yloxy)-1H-isoindole-1,3(2H)-dione
        Storage
        -20°C
        Shelf Life
        2 years
    • Properties
      • InChI Key
        NOGQTNDSZFYNTM-UHFFFAOYSA-N
        InChI
        InChI=1S/C16H12N2O5/c1-2-8-23-11-5-3-4-9-13(11)16(22)18(15(9)21)10-6-7-12(19)17-14(10)20/h1,3-5,10H,6-8H2,(H,17,19,20)
        Canonical SMILES
        C#CCOC1=CC=CC2=C1C(=O)N(C2=O)C3CCC(=O)NC3=O
Bio Calculators
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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g

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