PROTAC Library - PROTAC® / BOC Sciences

Structure	Catalog	Product Name	CAS	E3 Ligase	Target	Inquiry
	BPL-200933	SNIPER(ER)-88	2095244-88-3	XIAP	ER	Inquiry
Molecular Weight: 1088.38 Molecular Formula: C61H77N5O11S Boiling Point: 1120.7±65.0°C at 760 Torr Density: 1.206±0.06 g/cm3 Description: It reduces ERα levels in tumor xenografts and inhibits the growth of ERα-positive breast tumors in mice. It preferentially recruits X-linked IAP (XIAP) to degrade ERα via the ubiquitin-proteasome pathway.
	BPL-200934	SNIPER(PDE4)-9	2095244-56-5	XIAP	PDE4	Inquiry
Molecular Weight: 1137.19 Molecular Formula: C56H71Cl2N7O12S Boiling Point: 1195.3±65.0°C at 760 Torr Density: 1.295±0.06 g/cm3 Description: It preferentially recruits X-linked IAP (XIAP) to degrade PDE4 via the ubiquitin-proteasome pathway.
	BPL-200935	SNIPER(ER)-14	2095244-97-4	cIAP1	ER	Inquiry
Molecular Weight: 853.07 Molecular Formula: C49H64N4O9 Boiling Point: 1015.2±65.0°C at 760 Torr Density: 1.173±0.06 g/cm3 Description: It reduces ERα levels in tumor xenografts and inhibits the growth of ERα-positive breast tumors in mice. It recruits cIAP1 to degrade ERα via the ubiquitin-proteasome pathway.
	BPL-200936	SNIPER(ER)-21	2095245-07-9	IAP	ER	Inquiry
Molecular Weight: 1019.28 Molecular Formula: C61H74N6O8 Boiling Point: 1162.7±65.0°C at 760 Torr Density: 1.191±0.06 g/cm3 Description: It reduces ERα levels in tumor xenografts and inhibits the growth of ERα-positive breast tumors in mice. It recruits IAP to degrade ERα via the ubiquitin-proteasome pathway.
	BPL-200937	SNIPER(ER)-20	2095245-09-1	IAP	ER	Inquiry
Molecular Weight: 1063.35 Molecular Formula: C63H78N6O9 Boiling Point: 1181.4±65.0°C at 760 Torr Density: 1.187±0.06 g/cm3 Description: It reduces ERα levels in tumor xenografts and inhibits the growth of ERα-positive breast tumors in mice. It recruits IAP to degrade ERα via the ubiquitin-proteasome pathway.
	BPL-200938	SNIPER(ER)-19	2095245-11-5	IAP	ER	Inquiry
Molecular Weight: 1107.38 Molecular Formula: C65H82N6O10 Boiling Point: 1199.9±65.0°C at 760 Torr Density: 1.184±0.06 g/cm3 Description: It reduces ERα levels in tumor xenografts and inhibits the growth of ERα-positive breast tumors in mice. It recruits IAP to degrade ERα via the ubiquitin-proteasome pathway.
	BPL-200939	SNIPER(ER)-22	2095245-13-7	IAP	ER	Inquiry
Molecular Weight: 1151.46 Molecular Formula: C67H86N6O11 Boiling Point: 1218.3±65.0°C at 760 Torr Density: 1.182±0.06 g/cm3 Description: It reduces ERα levels in tumor xenografts and inhibits the growth of ERα-positive breast tumors in mice. It recruits IAP to degrade ERα via the ubiquitin-proteasome pathway.
	BPL-200940	SNIPER(ER)-29	2095244-69-0	IAP	ER	Inquiry
Molecular Weight: 1153.41 Molecular Formula: C64H76N6O12S Boiling Point: 1297.8±65.0°C at 760 Torr Density: 1.262±0.06 g/cm3 Description: It reduces ERα levels in tumor xenografts and inhibits the growth of ERα-positive breast tumors in mice. It recruits IAP to degrade ERα via the ubiquitin-proteasome pathway.
	BPL-200941	SNIPER(ER)-107		IAP	ER	Inquiry
Molecular Weight: 1064.42 Molecular Formula: C62H89N5O10 Description: It reduces ERα levels in tumor xenografts and inhibits the growth of ERα-positive breast tumors in mice. It recruits IAP to degrade ERα via the ubiquitin-proteasome pathway.
	BPL-200942	SNIPER(ER)-109		IAP	ER	Inquiry
Molecular Weight: 1107.40 Molecular Formula: C65H82N6O10 Description: It reduces ERα levels in tumor xenografts and inhibits the growth of ERα-positive breast tumors in mice. It recruits IAP to degrade ERα via the ubiquitin-proteasome pathway.
	BPL-200943	SNIPER(BRD)-2	2222355-70-4	cIAP1	BRD4	Inquiry
Molecular Weight: 1100.81 Molecular Formula: C55H70ClN9O9S2 Density: 1.38±0.1 g/cm3 Description: It induces the degradation of BRD4 via the ubiquitin-proteasome pathway.
	BPL-200944	SNIPER(ER)-104	2241690-02-6	XIAP	ER	Inquiry
Molecular Weight: 1055.28 Molecular Formula: C61H75FN6O9 Boiling Point: 1100.5±65.0°C at 760 Torr Density: 1.197±0.06 g/cm3 Description: It efficiently induces apoptosis in MCF-7 human breast cancer cells that require IAPs for continued cellular survival. It preferentially recruits XIAP, rather than cIAP1, to degrade ERα.
	BPL-200945	SNIPER(ER)-105	2241690-01-5	XIAP	ER	Inquiry
Molecular Weight: 1036.28 Molecular Formula: C60H73N7O9 Boiling Point: 1102.4±65.0°C at 760 Torr Density: 1.21±0.1 g/cm3 Description: It efficiently induces apoptosis in MCF-7 human breast cancer cells that require IAPs for continued cellular survival. It preferentially recruits XIAP, rather than cIAP1, to degrade ERα.
	BPL-200946	SNIPER(ER)-113	2241690-08-2	XIAP	ER	Inquiry
Molecular Weight: 1122.41 Molecular Formula: C66H83N5O11 Boiling Point: 1172.1±65.0°C at 760 Torr Density: 1.25±0.1 g/cm3 Description: It efficiently induces apoptosis in MCF-7 human breast cancer cells that require IAPs for continued cellular survival. It preferentially recruits XIAP, rather than cIAP1, to degrade ERα.
	BPL-200947	SNIPER(ER)-118	2241690-05-9	XIAP	ER	Inquiry
Molecular Weight: 1016.33 Molecular Formula: C60H81N5O9 Boiling Point: 1069.0±65.0°C at 760 Torr Density: 1.21±0.1 g/cm3 Description: It efficiently induces apoptosis in MCF-7 human breast cancer cells that require IAPs for continued cellular survival. It preferentially recruits XIAP, rather than cIAP1, to degrade ERα.
	BPL-200948	SNIPER(ER)-119	2241690-09-3	XIAP	ER	Inquiry
Molecular Weight: 1122.41 Molecular Formula: C66H83N5O11 Boiling Point: 1162.8±65.0°C at 760 Torr Density: 1.25±0.1 g/cm3 Description: It efficiently induces apoptosis in MCF-7 human breast cancer cells that require IAPs for continued cellular survival. It preferentially recruits XIAP, rather than cIAP1, to degrade ERα.
	BPL-200949	SNIPER(ER)-121	2241690-10-6	XIAP	ER	Inquiry
Molecular Weight: 1016.33 Molecular Formula: C60H81N5O9 Boiling Point: 1069.2±65.0°C at 760 Torr Density: 1.21±0.1 g/cm3 Description: It efficiently induces apoptosis in MCF-7 human breast cancer cells that require IAPs for continued cellular survival. It preferentially recruits XIAP, rather than cIAP1, to degrade ERα.
	BPL-200950	SNIPER(ER)-126	2222355-08-8	XIAP	ER	Inquiry
Molecular Weight: 1038.28 Molecular Formula: C61H75N5O10 Boiling Point: 1104.0±65.0°C at 760 Torr Density: 1.188±0.06 g/cm3 Description: It efficiently induces apoptosis in MCF-7 human breast cancer cells that require IAPs for continued cellular survival. It preferentially recruits XIAP, rather than cIAP1, to degrade ERα.
	BPL-200951	SNIPER(ER)-130	2222355-17-9	XIAP	ER	Inquiry
Molecular Weight: 1110.39 Molecular Formula: C62H75N7O10S Boiling Point: 1160.7±65.0°C at 760 Torr Density: 1.235±0.06 g/cm3 Description: It efficiently induces apoptosis in MCF-7 human breast cancer cells that require IAPs for continued cellular survival. It preferentially recruits XIAP, rather than cIAP1, to degrade ERα.
	BPL-200952	SNIPER(ER)-131	2241690-06-0	XIAP	ER	Inquiry
Molecular Weight: 1091.34 Molecular Formula: C58H74N8O11S Description: It efficiently induces apoptosis in MCF-7 human breast cancer cells that require IAPs for continued cellular survival. It preferentially recruits XIAP, rather than cIAP1, to degrade ERα.