PROTAC Library - PROTAC® / BOC Sciences

Structure	Catalog	Product Name	CAS	E3 Ligase	Target	Inquiry
	BPL-200953	SNIPER(ER)-134	2241690-07-1	XIAP	ER	Inquiry
Molecular Weight: 1122.41 Molecular Formula: C66H83N5O11 Boiling Point: 1171.3±65.0°C at 760 Torr Density: 1.25±0.1 g/cm3 Description: It efficiently induces apoptosis in MCF-7 human breast cancer cells that require IAPs for continued cellular survival. It preferentially recruits XIAP, rather than cIAP1, to degrade ERα.
	BPL-200954	SNIPER(ER)-136	2241690-04-8	XIAP	ER	Inquiry
Molecular Weight: 1176.46 Molecular Formula: C68H78FN5O10S Density: 1.227±0.06 g/cm3 Description: It efficiently induces apoptosis in MCF-7 human breast cancer cells that require IAPs for continued cellular survival. It preferentially recruits XIAP, rather than cIAP1, to degrade ERα.
	BPL-200955	SNIPER(AR)-2	2113688-32-5	cIAP1	AR	Inquiry
Molecular Weight: 819.99 Molecular Formula: C46H57N7O7 Boiling Point: 1073.2±65.0°C at 760 Torr Density: 1.21±0.1 g/cm3 Description: It is a protein degradation inducer of androgen receptor by conjugation of an androgen receptor ligand and an inhibitor of apoptosis protein ligand.
	BPL-200956	SNIPER(AR)-8	2113688-33-6	cIAP1	AR	Inquiry
Molecular Weight: 921.01 Molecular Formula: C43H55F3N6O11S Boiling Point: 1153.6±65.0°C at 760 Torr Density: 1.36±0.1 g/cm3 Description: It is a protein degradation inducer of androgen receptor by conjugation of an androgen receptor ligand and an inhibitor of apoptosis protein ligand.
	BPL-200957	SNIPER(AR)-23	2113688-34-7	cIAP1	AR	Inquiry
Molecular Weight: 863.98 Molecular Formula: C45H56F3N7O7 Boiling Point: 1039.3±65.0°C at 760 Torr Density: 1.26±0.1 g/cm3 Description: It is a protein degradation inducer of androgen receptor by conjugation of an androgen receptor ligand and an inhibitor of apoptosis protein ligand.
	BPL-200958	SNIPER(AR)-26	2113688-35-8	cIAP1	AR	Inquiry
Molecular Weight: 844.45 Molecular Formula: C45H58ClN7O7 Boiling Point: 1049.6±65.0°C at 760 Torr Density: 1.24±0.1 g/cm3 Description: It is a protein degradation inducer of androgen receptor by conjugation of an androgen receptor ligand and an inhibitor of apoptosis protein ligand.
	BPL-200959	SNIPER(AR)-27	2113688-58-5	cIAP1	AR	Inquiry
Molecular Weight: 830.43 Molecular Formula: C44H56ClN7O7 Boiling Point: 1041.4±65.0°C at 760 Torr Density: 1.25±0.1 g/cm3 Description: It is a protein degradation inducer of androgen receptor by conjugation of an androgen receptor ligand and an inhibitor of apoptosis protein ligand.
	BPL-200960	SNIPER(AR)-12	2113688-19-8	IAP	AR	Inquiry
Molecular Weight: 1074.34 Molecular Formula: C62H75N9O8 Boiling Point: 1251.2±65.0°C at 760 Torr Density: 1.23±0.1 g/cm3 Description: It is a protein degradation inducer of androgen receptor by conjugation of an androgen receptor ligand and an inhibitor of apoptosis protein ligand.
	BPL-200961	SNIPER(AR)-31	2113688-22-3	cIAP1	AR	Inquiry
Molecular Weight: 967.21 Molecular Formula: C54H62N8O7S Boiling Point: 1131.4±65.0°C at 760 Torr Density: 1.28±0.1 g/cm3 Description: It is a protein degradation inducer of androgen receptor by conjugation of an androgen receptor ligand and an inhibitor of apoptosis protein ligand.
	BPL-200962	SNIPER(AR)-60	2113688-60-9	cIAP1	AR	Inquiry
Molecular Weight: 978.23 Molecular Formula: C56H63N7O7S Boiling Point: 1100.0±65.0°C at 760 Torr Density: 1.23±0.1 g/cm3 Description: It is a protein degradation inducer of androgen receptor by conjugation of an androgen receptor ligand and an inhibitor of apoptosis protein ligand.
	BPL-200963	SNIPER(AR)-70	2113688-62-1	cIAP1	AR	Inquiry
Molecular Weight: 982.26 Molecular Formula: C56H67N7O7S Boiling Point: 1097.4±65.0°C at 760 Torr Density: 1.24±0.1 g/cm3 Description: It is a protein degradation inducer of androgen receptor by conjugation of an androgen receptor ligand and an inhibitor of apoptosis protein ligand.
	BPL-200964	SNIPER(AR)-53	2113688-44-9	cIAP1	AR	Inquiry
Molecular Weight: 984.23 Molecular Formula: C55H65N7O8S Boiling Point: 1105.1±65.0°C at 760 Torr Density: 1.26±0.1 g/cm3 Description: It is a protein degradation inducer of androgen receptor by conjugation of an androgen receptor ligand and an inhibitor of apoptosis protein ligand.
	BPL-200965	SNIPER(AR)-52	2113688-45-0	cIAP1	AR	Inquiry
Molecular Weight: 940.18 Molecular Formula: C53H61N7O7S Boiling Point: 1085.5±65.0°C at 760 Torr Density: 1.26±0.1 g/cm3 Description: It is a protein degradation inducer of androgen receptor by conjugation of an androgen receptor ligand and an inhibitor of apoptosis protein ligand.
	BPL-200966	SNIPER(AR)-171	2113688-46-1	cIAP1	AR	Inquiry
Molecular Weight: 1028.29 Molecular Formula: C57H69N7O9S Boiling Point: 1123.9±65.0°C at 760 Torr Density: 1.25±0.1 g/cm3 Description: It is a protein degradation inducer of androgen receptor by conjugation of an androgen receptor ligand and an inhibitor of apoptosis protein ligand.
	BPL-200967	SNIPER(AR)-65	2113688-47-2	cIAP1	AR	Inquiry
Molecular Weight: 984.23 Molecular Formula: C55H65N7O8S Boiling Point: 1099.3±65.0°C at 760 Torr Density: 1.26±0.1 g/cm3 Description: It is a protein degradation inducer of androgen receptor by conjugation of an androgen receptor ligand and an inhibitor of apoptosis protein ligand.
	BPL-200968	SNIPER(AR)-66	2113688-54-1	cIAP1	AR	Inquiry
Molecular Weight: 988.22 Molecular Formula: C57H61N7O7S Boiling Point: 1136.5±65.0°C at 760 Torr Density: 1.27±0.1 g/cm3 Description: It is a protein degradation inducer of androgen receptor by conjugation of an androgen receptor ligand and an inhibitor of apoptosis protein ligand.
	BPL-200969	SNIPER(AR)-67	2113688-55-2	cIAP1	AR	Inquiry
Molecular Weight: 988.22 Molecular Formula: C57H61N7O7S Boiling Point: 1135.6±65.0°C at 760 Torr Density: 1.27±0.1 g/cm3 Description: It is a protein degradation inducer of androgen receptor by conjugation of an androgen receptor ligand and an inhibitor of apoptosis protein ligand.
	BPL-200970	SNIPER(AR)-68	2113688-56-3	cIAP1	AR	Inquiry
Molecular Weight: 988.22 Molecular Formula: C57H61N7O7S Boiling Point: 1125.9±65.0°C at 760 Torr Density: 1.27±0.1 g/cm3 Description: It is a protein degradation inducer of androgen receptor by conjugation of an androgen receptor ligand and an inhibitor of apoptosis protein ligand.
	BPL-200971	N-(4-(3-(2,6-Difluoro-3-(propylsulfonamido)benzoyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)benzyl)-5-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)pentanamide	2417296-82-1	CRBN	BRAF V600E	Inquiry
Molecular Weight: 839.88 Molecular Formula: C42H39F2N7O8S Density: 1.470±0.06 g/cm3 Description: It is a thalidomide-based heterobifunctional PROTAC that induces selective degradation of BRAF-V600E, but not the wild-type BRAF.
	BPL-200972	N-(4-(3-(2,6-Difluoro-3-(propylsulfonamido)benzoyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)benzyl)-4-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)butanamide		CRBN	BRAF V600E	Inquiry
Molecular Weight: 825.85 Molecular Formula: C41H37F2N7O8S Description: It is a thalidomide-based heterobifunctional PROTAC that induces selective degradation of BRAF-V600E, but not the wild-type BRAF.