PROTAC Library - PROTAC® / BOC Sciences

Structure	Catalog	Product Name	CAS	E3 Ligase	Target	Inquiry
	BPL-200893	(S)-22-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-23,23-dimethyl-5,20-dioxo-8,11,14,17-tetraoxa-4,21-diazatetracosyl (2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl)carbamate	2509359-71-9	VHL	Cdc20	Inquiry
Molecular Weight: 1031.46 Molecular Formula: C44H62Cl3N9O11S Density: 1.337±0.06 g/cm3 Description: It deprives the mitotic role for Cdc20-APC/C by either inhibition of Cdc20-APC/C activity or elimination of Cdc20 protein via induced protein degradation.
	BPL-200894	CP5V	2509359-75-3	VHL	Cdc20	Inquiry
Molecular Weight: 1075.51 Molecular Formula: C46H66Cl3N9O12S Density: 1.326±0.06 g/cm3 Description: It deprives the mitotic role for Cdc20-APC/C by either inhibition of Cdc20-APC/C activity or elimination of Cdc20 protein via induced protein degradation.
	BPL-200895	(S)-28-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-29,29-dimethyl-5,26-dioxo-8,11,14,17,20,23-hexaoxa-4,27-diazatriacontyl (2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl)carbamate	2509359-77-5	VHL	Cdc20	Inquiry
Molecular Weight: 1119.56 Molecular Formula: C48H70Cl3N9O13S Density: 1.317±0.06 g/cm3 Description: It deprives the mitotic role for Cdc20-APC/C by either inhibition of Cdc20-APC/C activity or elimination of Cdc20 protein via induced protein degradation.
	BPL-200896	(S)-31-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-32,32-dimethyl-5,29-dioxo-8,11,14,17,20,23,26-heptaoxa-4,30-diazatritriacontyl (2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl)carbamate	2509359-79-7	VHL	Cdc20	Inquiry
Molecular Weight: 1163.62 Molecular Formula: C50H74Cl3N9O14S Density: 1.308±0.06 g/cm3 Description: It deprives the mitotic role for Cdc20-APC/C by either inhibition of Cdc20-APC/C activity or elimination of Cdc20 protein via induced protein degradation.
	BPL-200897	(S)-37-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-38,38-dimethyl-5,35-dioxo-8,11,14,17,20,23,26,29,32-nonaoxa-4,36-diazanonatriacontyl (2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl)carbamate	2509359-84-4	VHL	Cdc20	Inquiry
Molecular Weight: 1251.72 Molecular Formula: C54H82Cl3N9O16S Density: 1.293±0.06 g/cm3 Description: It deprives the mitotic role for Cdc20-APC/C by either inhibition of Cdc20-APC/C activity or elimination of Cdc20 protein via induced protein degradation.
	BPL-200898	18-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-5,14-dioxo-8,11-dioxa-4,15-diazaoctadecyl (2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl)carbamate	2509359-87-7	CRBN	Cdc20	Inquiry
Molecular Weight: 844.11 Molecular Formula: C34H41Cl3N8O11 Density: 1.451±0.06 g/cm3 Description: It deprives the mitotic role for Cdc20-APC/C by either inhibition of Cdc20-APC/C activity or elimination of Cdc20 protein via induced protein degradation.
	BPL-200899	21-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-5,17-dioxo-8,11,14-trioxa-4,18-diazahenicosyl (2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl)carbamate	2509359-89-9	CRBN	Cdc20	Inquiry
Molecular Weight: 888.16 Molecular Formula: C36H45Cl3N8O12 Density: 1.430±0.06 g/cm3 Description: It deprives the mitotic role for Cdc20-APC/C by either inhibition of Cdc20-APC/C activity or elimination of Cdc20 protein via induced protein degradation.
	BPL-200900	27-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-5,23-dioxo-8,11,14,17,20-pentaoxa-4,24-diazaheptacosyl (2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl)carbamate	2509359-91-3	CRBN	Cdc20	Inquiry
Molecular Weight: 976.27 Molecular Formula: C40H53Cl3N8O14 Density: 1.395±0.06 g/cm3 Description: It deprives the mitotic role for Cdc20-APC/C by either inhibition of Cdc20-APC/C activity or elimination of Cdc20 protein via induced protein degradation.
	BPL-200901	1-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-4,16-dioxo-7,10,13-trioxa-3,17-diazaicosan-20-yl (2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl)carbamate	2509360-01-2	CRBN	Cdc20	Inquiry
Molecular Weight: 874.13 Molecular Formula: C35H43Cl3N8O12 Density: 1.446±0.06 g/cm3 Description: It deprives the mitotic role for Cdc20-APC/C by either inhibition of Cdc20-APC/C activity or elimination of Cdc20 protein via induced protein degradation.
	BPL-200902	1-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-4,25-dioxo-7,10,13,16,19,22-hexaoxa-3,26-diazanonacosan-29-yl (2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl)carbamate	2509360-02-3	CRBN	Cdc20	Inquiry
Molecular Weight: 1006.29 Molecular Formula: C41H55Cl3N8O15 Density: 1.392±0.06 g/cm3 Description: It deprives the mitotic role for Cdc20-APC/C by either inhibition of Cdc20-APC/C activity or elimination of Cdc20 protein via induced protein degradation.
	BPL-200903	30-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-5,26-dioxo-8,11,14,17,20,23-hexaoxa-4,27-diazatriacontyl (2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl)carbamate	2509359-95-7	CRBN	Cdc20	Inquiry
Molecular Weight: 1020.32 Molecular Formula: C42H57Cl3N8O15 Density: 1.380±0.06 g/cm3 Description: It deprives the mitotic role for Cdc20-APC/C by either inhibition of Cdc20-APC/C activity or elimination of Cdc20 protein via induced protein degradation.
	BPL-200904	39-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-5,35-dioxo-8,11,14,17,20,23,26,29,32-nonaoxa-4,36-diazanonatriacontyl (2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl)carbamate	2509359-97-9	CRBN	Cdc20	Inquiry
Molecular Weight: 1152.48 Molecular Formula: C48H69Cl3N8O18 Density: 1.344±0.06 g/cm3 Description: It deprives the mitotic role for Cdc20-APC/C by either inhibition of Cdc20-APC/C activity or elimination of Cdc20 protein via induced protein degradation.
	BPL-200905	1-(4-(((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)methyl)-1H-1,2,3-triazol-1-yl)-18-oxo-3,6,9,12,15-pentaoxa-19-azadocosan-22-yl (2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl)carbamate	2509360-05-6	CRBN	Cdc20	Inquiry
Molecular Weight: 972.24 Molecular Formula: C39H49Cl3N10O13 Density: 1.52±0.1 g/cm3 Description: It deprives the mitotic role for Cdc20-APC/C by either inhibition of Cdc20-APC/C activity or elimination of Cdc20 protein via induced protein degradation.
	BPL-200906	CM09	2244684-47-5	VHL	VHL	Inquiry
Molecular Weight: 1091.36 Molecular Formula: C54H74N8O12S2 Boiling Point: 1261.7±65.0°C at 760 Torr Density: 1.279±0.06 g/cm3 Description: It is a homo-protac, a bivalent small molecule dimerizer of VHL E3 ubiquitin ligase that can induce self-degradation.
	BPL-200907	CM10	2244684-48-6	VHL	VHL	Inquiry
Molecular Weight: 1135.42 Molecular Formula: C56H78N8O13S2 Boiling Point: 1277.4±65.0°C at 760 Torr Density: 1.272±0.06 g/cm3 Description: It is a homo-protac, a bivalent small molecule dimerizer of VHL E3 ubiquitin ligase that can induce self-degradation.
	BPL-200908	CMP106	2244684-52-2	VHL	VHL	Inquiry
Molecular Weight: 1179.47 Molecular Formula: C58H82N8O14S2 Boiling Point: 1294.9±65.0°C at 760 Torr Density: 1.262±0.06 g/cm3 Description: It is a homo-protac, a bivalent small molecule dimerizer of VHL E3 ubiquitin ligase that can induce self-degradation.
	BPL-200909	CMP108	2244684-53-3	VHL	VHL	Inquiry
Molecular Weight: 1281.57 Molecular Formula: C64H84N10O14S2 Boiling Point: 1398.6±65.0°C at 760 Torr Density: 1.36±0.1 g/cm3 Description: It is a homo-protac, a bivalent small molecule dimerizer of VHL E3 ubiquitin ligase that can induce self-degradation.
	BPL-200910	CMP112	2244684-54-4	VHL	VHL	Inquiry
Molecular Weight: 1179.47 Molecular Formula: C58H82N8O14S2 Boiling Point: 1294.1±65.0°C at 760 Torr Density: 1.264±0.06 g/cm3 Description: It is a homo-protac, a bivalent small molecule dimerizer of VHL E3 ubiquitin ligase that can induce self-degradation.
	BPL-200911	CMP113	2244684-55-5	VHL	VHL	Inquiry
Molecular Weight: 1230.52 Molecular Formula: C61H83N9O14S2 Boiling Point: 1346.4±65.0°C at 760 Torr Density: 1.34±0.1 g/cm3 Description: It is a homo-protac, a bivalent small molecule dimerizer of VHL E3 ubiquitin ligase that can induce self-degradation.
	BPL-200912	IY-IY-pom	2569202-29-3	CRBN	TRKC	Inquiry
Molecular Weight: 1447.68 Molecular Formula: C71H94N22O12 Density: 1.47±0.1 g/cm3 Description: It is a potent proteolysis targeting chimeric (PROTAC) for TrkC degradation in metastatic breast cancer cells.