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E3 Ligase
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Structure Catalog Product Name CAS E3 Ligase Target Inquiry
(2S,4R)-4-Hydroxy-1-((S)-2-(8-(4-((2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)octanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200833 (2S,4R)-4-Hydroxy-1-((S)-2-(8-(4-((2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)octanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2462013-23-4

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ER

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Molecular Weight: 973.23

Molecular Formula: C53H60N6O8S2

Density: 1.32±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(2-(2-(4-((2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200834 (2S,4R)-4-Hydroxy-1-((S)-2-(2-(2-(4-((2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2462013-85-8

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ER

 Inquiry

Molecular Weight: 933.12

Molecular Formula: C49H52N6O9S2

Density: 1.37±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(2-(2-(2-(4-((2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)ethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200835 (2S,4R)-4-Hydroxy-1-((S)-2-(2-(2-(2-(4-((2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)ethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2462014-58-8

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ER

 Inquiry

Molecular Weight: 977.18

Molecular Formula: C51H56N6O10S2

Density: 1.36±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-1-((S)-2-(tert-Butyl)-14-(4-((E)-(2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200836 (2S,4R)-1-((S)-2-(tert-Butyl)-14-(4-((E)-(2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2462015-21-8

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ER

 Inquiry

Molecular Weight: 1021.23

Molecular Formula: C53H60N6O11S2

Density: 1.35±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-1-((S)-2-(tert-Butyl)-17-(4-((E)-(2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200837 (2S,4R)-1-((S)-2-(tert-Butyl)-17-(4-((E)-(2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461994-82-9

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ER

 Inquiry

Molecular Weight: 1065.28

Molecular Formula: C55H64N6O12S2

Density: 1.34±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-1-((S)-2-(tert-Butyl)-20-(4-((E)-(2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15,18-pentaoxa-3-azaicosanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200838 (2S,4R)-1-((S)-2-(tert-Butyl)-20-(4-((E)-(2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15,18-pentaoxa-3-azaicosanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2462016-97-1

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ER

 Inquiry

Molecular Weight: 1109.33

Molecular Formula: C57H68N6O13S2

Density: 1.33±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-1-((S)-2-(tert-Butyl)-23-(4-((E)-(2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15,18,21-hexaoxa-3-azatricosanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200839 (2S,4R)-1-((S)-2-(tert-Butyl)-23-(4-((E)-(2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15,18,21-hexaoxa-3-azatricosanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2462018-90-0

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ER

 Inquiry

Molecular Weight: 1153.39

Molecular Formula: C59H72N6O14S2

Density: 1.32±0.1 g/cm3

Description: It is a potent ER degrader.
AM-A2 BPL-200840 AM-A2 2423867-01-8

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ER

 Inquiry

Molecular Weight: 1022.26

Molecular Formula: C57H59N5O9S2

Boiling Point: 1258.5±65.0°C at 760 Torr

Density: 1.313±0.06 g/cm3

Description: It is a potent ER degrader.
AM-A3 BPL-200841 AM-A3 2423867-02-9

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ER

 Inquiry

Molecular Weight: 1036.29

Molecular Formula: C58H61N5O9S2

Boiling Point: 1260.2±65.0°C at 760 Torr

Density: 1.303±0.06 g/cm3

Description: It is a potent ER degrader.
AM-A4 BPL-200842 AM-A4 2423867-03-0

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ER

 Inquiry

Molecular Weight: 1050.31

Molecular Formula: C59H63N5O9S2

Boiling Point: 1262.3±65.0°C at 760 Torr

Density: 1.294±0.06 g/cm3

Description: It is a potent ER degrader.
DAT1 BPL-200843 DAT1 2381196-64-9

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SGK3

 Inquiry

Molecular Weight: 1101.29

Molecular Formula: C53H65FN10O11S2

Density: 1.346±0.06 g/cm3

Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
DAT2 BPL-200844 DAT2 2381196-65-0

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SGK3

 Inquiry

Molecular Weight: 1147.78

Molecular Formula: C54H67ClN10O12S2

Density: 1.351±0.06 g/cm3

Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
DAT3 BPL-200845 DAT3 2381196-66-1

CRBN

SGK3

 Inquiry

Molecular Weight: 987.04

Molecular Formula: C46H51FN10O12S

Density: 1.439±0.06 g/cm3

Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
DAT4 BPL-200846 DAT4 2381196-68-3

CRBN

SGK3

 Inquiry

Molecular Weight: 1033.52

Molecular Formula: C47H53ClN10O13S

Density: 1.440±0.06 g/cm3

Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
DAT5 BPL-200847 DAT5 2381196-70-7

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SGK3

 Inquiry

Molecular Weight: 1057.24

Molecular Formula: C51H61FN10O10S2

Density: 1.358±0.06 g/cm3

Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
DAT6 BPL-200848 DAT6 2381196-71-8

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SGK3

 Inquiry

Molecular Weight: 1145.35

Molecular Formula: C55H69FN10O12S2

Density: 1.336±0.06 g/cm3

Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
DAT7 BPL-200849 DAT7 2381196-72-9

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SGK3

 Inquiry

Molecular Weight: 1189.40

Molecular Formula: C57H73FN10O13S2

Density: 1.326±0.06 g/cm3

Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
DAT9 BPL-200850 DAT9 2381196-73-0

VHL

SGK3

 Inquiry

Molecular Weight: 1201.45

Molecular Formula: C59H77FN10O12S2

Density: 1.301±0.06 g/cm3

Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
DAT10 BPL-200851 DAT10 2381196-74-1

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SGK3

 Inquiry

Molecular Weight: 1169.46

Molecular Formula: C59H77FN10O10S2

Density: 1.284±0.06 g/cm3

Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
DAT11 BPL-200852 DAT11 2381196-75-2

VHL

SGK3

 Inquiry

Molecular Weight: 1247.94

Molecular Formula: C60H79ClN10O13S2

Density: 1.307±0.06 g/cm3

Description: It is an isoform-specific SGK3 kinase PROTAC degrader.

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