PROTAC Library - PROTAC® / BOC Sciences

Structure	Catalog	Product Name	CAS	E3 Ligase	Target	Inquiry
	BPL-200833	(2S,4R)-4-Hydroxy-1-((S)-2-(8-(4-((2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)octanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide	2462013-23-4	VHL	ER	Inquiry
Molecular Weight: 973.23 Molecular Formula: C53H60N6O8S2 Density: 1.32±0.1 g/cm3 Description: It is a potent ER degrader.
	BPL-200834	(2S,4R)-4-Hydroxy-1-((S)-2-(2-(2-(4-((2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide	2462013-85-8	VHL	ER	Inquiry
Molecular Weight: 933.12 Molecular Formula: C49H52N6O9S2 Density: 1.37±0.1 g/cm3 Description: It is a potent ER degrader.
	BPL-200835	(2S,4R)-4-Hydroxy-1-((S)-2-(2-(2-(2-(4-((2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)ethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide	2462014-58-8	VHL	ER	Inquiry
Molecular Weight: 977.18 Molecular Formula: C51H56N6O10S2 Density: 1.36±0.1 g/cm3 Description: It is a potent ER degrader.
	BPL-200836	(2S,4R)-1-((S)-2-(tert-Butyl)-14-(4-((E)-(2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide	2462015-21-8	VHL	ER	Inquiry
Molecular Weight: 1021.23 Molecular Formula: C53H60N6O11S2 Density: 1.35±0.1 g/cm3 Description: It is a potent ER degrader.
	BPL-200837	(2S,4R)-1-((S)-2-(tert-Butyl)-17-(4-((E)-(2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide	2461994-82-9	VHL	ER	Inquiry
Molecular Weight: 1065.28 Molecular Formula: C55H64N6O12S2 Density: 1.34±0.1 g/cm3 Description: It is a potent ER degrader.
	BPL-200838	(2S,4R)-1-((S)-2-(tert-Butyl)-20-(4-((E)-(2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15,18-pentaoxa-3-azaicosanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide	2462016-97-1	VHL	ER	Inquiry
Molecular Weight: 1109.33 Molecular Formula: C57H68N6O13S2 Density: 1.33±0.1 g/cm3 Description: It is a potent ER degrader.
	BPL-200839	(2S,4R)-1-((S)-2-(tert-Butyl)-23-(4-((E)-(2-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15,18,21-hexaoxa-3-azatricosanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide	2462018-90-0	VHL	ER	Inquiry
Molecular Weight: 1153.39 Molecular Formula: C59H72N6O14S2 Density: 1.32±0.1 g/cm3 Description: It is a potent ER degrader.
	BPL-200840	AM-A2	2423867-01-8	VHL	ER	Inquiry
Molecular Weight: 1022.26 Molecular Formula: C57H59N5O9S2 Boiling Point: 1258.5±65.0°C at 760 Torr Density: 1.313±0.06 g/cm3 Description: It is a potent ER degrader.
	BPL-200841	AM-A3	2423867-02-9	VHL	ER	Inquiry
Molecular Weight: 1036.29 Molecular Formula: C58H61N5O9S2 Boiling Point: 1260.2±65.0°C at 760 Torr Density: 1.303±0.06 g/cm3 Description: It is a potent ER degrader.
	BPL-200842	AM-A4	2423867-03-0	VHL	ER	Inquiry
Molecular Weight: 1050.31 Molecular Formula: C59H63N5O9S2 Boiling Point: 1262.3±65.0°C at 760 Torr Density: 1.294±0.06 g/cm3 Description: It is a potent ER degrader.
	BPL-200843	DAT1	2381196-64-9	VHL	SGK3	Inquiry
Molecular Weight: 1101.29 Molecular Formula: C53H65FN10O11S2 Density: 1.346±0.06 g/cm3 Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
	BPL-200844	DAT2	2381196-65-0	VHL	SGK3	Inquiry
Molecular Weight: 1147.78 Molecular Formula: C54H67ClN10O12S2 Density: 1.351±0.06 g/cm3 Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
	BPL-200845	DAT3	2381196-66-1	CRBN	SGK3	Inquiry
Molecular Weight: 987.04 Molecular Formula: C46H51FN10O12S Density: 1.439±0.06 g/cm3 Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
	BPL-200846	DAT4	2381196-68-3	CRBN	SGK3	Inquiry
Molecular Weight: 1033.52 Molecular Formula: C47H53ClN10O13S Density: 1.440±0.06 g/cm3 Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
	BPL-200847	DAT5	2381196-70-7	VHL	SGK3	Inquiry
Molecular Weight: 1057.24 Molecular Formula: C51H61FN10O10S2 Density: 1.358±0.06 g/cm3 Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
	BPL-200848	DAT6	2381196-71-8	VHL	SGK3	Inquiry
Molecular Weight: 1145.35 Molecular Formula: C55H69FN10O12S2 Density: 1.336±0.06 g/cm3 Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
	BPL-200849	DAT7	2381196-72-9	VHL	SGK3	Inquiry
Molecular Weight: 1189.40 Molecular Formula: C57H73FN10O13S2 Density: 1.326±0.06 g/cm3 Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
	BPL-200850	DAT9	2381196-73-0	VHL	SGK3	Inquiry
Molecular Weight: 1201.45 Molecular Formula: C59H77FN10O12S2 Density: 1.301±0.06 g/cm3 Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
	BPL-200851	DAT10	2381196-74-1	VHL	SGK3	Inquiry
Molecular Weight: 1169.46 Molecular Formula: C59H77FN10O10S2 Density: 1.284±0.06 g/cm3 Description: It is an isoform-specific SGK3 kinase PROTAC degrader.
	BPL-200852	DAT11	2381196-75-2	VHL	SGK3	Inquiry
Molecular Weight: 1247.94 Molecular Formula: C60H79ClN10O13S2 Density: 1.307±0.06 g/cm3 Description: It is an isoform-specific SGK3 kinase PROTAC degrader.