Pomalidomide-PEG3-CO2H

 CAS No.: 2138440-82-9  Cat No.: BP-100020  Purity: ≥98% 4.5  

Pomalidomide-PEG3-C2-carboxylic acid is a PROTAC block consist of Pomalidomide linked to PEG with a carboxylic acid functional group for conjugation reactions.

Pomalidomide-PEG3-CO2H

Structure of 2138440-82-9

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Category
E3 Ligase Ligand-Linker Conjugate
Molecular Formula
C22H27N3O9
Molecular Weight
477.46
Appearance
Yellow Solid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥98%
Solubility
Soluble in DMSO
Appearance
Yellow Solid
ShelfLife
2 years
Storage
solvent: -80°C 12 months; Powder: -20°C 3 years
IUPACName
3-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]propanoic acid
Synonyms
Pomalidomide-PEG3-CO2H; Thalidomide-NH-PEG3-propionic acid; 3-(2-(2-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethoxy)propanoic acid; Pomalidomide-linker 2
Boiling Point
757.8±60.0°C (Predicted)
Density
1.417±0.06 g/cm3 (Predicted)
InChI Key
QBYOEHKZQIFBGV-UHFFFAOYSA-N
InChI
InChI=1S/C22H27N3O9/c26-17-5-4-16(20(29)24-17)25-21(30)14-2-1-3-15(19(14)22(25)31)23-7-9-33-11-13-34-12-10-32-8-6-18(27)28/h1-3,16,23H,4-13H2,(H,27,28)(H,24,26,29)
Canonical SMILES
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCOCCC(=O)O

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: Pomalidomide-PEG2-C2-NH2 | NH2-PEG2-CH2-Boc | Hydroxy-PEG3-t-butyl ester | Pomalidomide-linker 3 | Fmoc-PEG8-NHS ester | m-PEG2-O-Ph-NH2 | Tos-PEG4-COOtBu | Tos-PEG3-alcohol | Pomalidomide-C4-OH | Pomalidomide-PEG3-CO2H

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