SR-1114

 Cat No.: BP-400189 4.5  

SR-1114 is a first-in-class PROTAC ENL degrader. It induces rapid and CRBN-dependent degradation of ENL with DC50 values in different cell lines. It shows efficient degradation in MV4;11 cells (150 nM DC50), MOLM-13 cells (311 nM DC50), and OCI/AML-2 cells (1.65 μM DC50).

SR-1114

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Category
PROTAC
Molecular Formula
C39H42N8O11S
Molecular Weight
830.86

* For research and manufacturing use only. Not for human or clinical use.

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Store at -20°C

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: PROTAC ERRα ligand 1 | Biotin-Teg-amine TFA | Biotin-PEG5-azide | 2,5,8,11,14,17-Hexaoxa-19-nonadecanyl Methanesulfonate | MS4078 | ARV-771 | Biotin-PEG4-Picolyl azide | PROTAC ERα Degrader-2 | PROTAC BET degrader-2 | Biotin-PEG3-NHS ester | SR-1114

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