MS177

Name: MS177
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 2225938-86-1

Cat No.: BP-400173 4.5

MS177 is a potent and rapidly acting EZH2 degrader. It is a PROTAC molecule that combines a CRBN ligand, a linker, and an effective enzymatic EZH2 inhibitor C24 (C24 IC50: 12 nM). MS177 efficiently depletes EZH2-PRC2 and non-classical EZH2-cMyc complexes. It inhibits leukemia cell growth, induces apoptosis, and causes cell cycle arrest.

Structure of 2225938-86-1

Quality
Assurance

Worldwide
Delivery

24/7 Customer
Support

Category

PROTAC

Molecular Formula

C48H55N11O8

Molecular Weight

914.02

Appearance

Solid

* For research and manufacturing use only. Not for human or clinical use.

Size	Price	Stock	Quantity
--	$--	In stock

Looking for different specifications? Click to request a custom quote!

Capabilities & Facilities

mg to g scale for early stage;
CDMO and CMO support.
24/7 customer service;

100% quality assurance;
Efficient global delivery;
Over 95% customer satisfaction.

Popular Publications Citing BOC Sciences Products

Specification
QA & Reviews

Appearance

Solid

Storage

Store at -20°C

Stock concentration: *

Desired final volume: *

Desired concentration: *

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C₁V₁ = C₂V₂