ITM2B (Integral Membrane Protein 2B)

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ITM2B (Integral Membrane Protein 2B) is a protein encoded by the ITM2B gene in the human body. ITM2B or BRI2 is a gene located on chromosome 13. The gene encodes a transmembrane protein, which is processed at the C-terminal of furin or furin-like proteases to produce secreted small peptides, thus inhibiting the deposition of β-amyloid protein. Mutations in the size of the peptide that causes the C-terminal extension of the protein to increase secretion are associated with two neurogenic diseases, familial British dementia, and familial Danish dementia. Diseases associated with ITM2B include retinal dystrophy, retinal dysfunction, and ganglion cell abnormalities, and cerebral amyloid angiopathy.

Cat.No.Product NameSourceSpeciesTagMolecular Weight
BP-801290Recombinant Human ITM2B, His-taggedHEK293HumanHis
BP-801291Recombinant Rhesus monkey ITM2B Protein, His-taggedMammalian CellsRhesus monkeyHis
BP-801292Recombinant Rat ITM2B ProteinMammalian CellsRatHis
BP-801293Recombinant Human ITM2B Protein, GST-taggedWheat GermHumanGST
BP-801294Recombinant Cynomolgus ITM2B Protein, His-taggedMammalian CellsCynomolgusHis
BP-801295Recombinant Chicken ITM2BMammalian CellsChickenHis
BP-801296Recombinant Mouse ITM2B ProteinMammalian CellsMouseHis

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