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Bis-PEG8-acid - CAS 1246189-43-4

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Bis-PEG8-acid is a PEG linker containing two terminal carboxylic acid groups. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

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Molecular Formula

C20H38O12

Molecular Weight

470.51

Bis-PEG8-acid

- Specification
  - Related CAS
    
    51178-68-8 (polymer)
    
    Purity
    
    ≥95%
    
    Solubility
    
    Soluble in DMSO
    
    Appearance
    
    Pale Yellow or Colorless Oily Matter
    
    Shelf Life
    
    -20°C 3 years powder; -80°C 2 years in solvent
    
    Storage
    
    Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
    
    Shipping
    
    Room temperature, or blue ice upon request.
    
    IUPAC Name
    
    3-[2-[2-[2-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
    
    Synonyms
    
    HOOC-PEG7-CH2CH2COOH; HOOCCH2CH2O-PEG7-CH2CH2COOH; 4,7,10,13,16,19,22,25-Octaoxaoctacosanedioic acid; Bis-PEG8-COOH; 4,7,10,13,16,19,22,25-Octaoxaoctacosane-1,28-dioic Acid; Di-Acid-PEG8
- Properties
  - Boiling Point
    
    601.8±55.0°C (Predicted)
    
    Density
    
    1.179±0.06 g/cm3 (Predicted)
    
    InChI Key
    
    IRTAMFHIULAGCS-UHFFFAOYSA-N
    
    InChI
    
    InChI=1S/C20H38O12/c21-19(22)1-3-25-5-7-27-9-11-29-13-15-31-17-18-32-16-14-30-12-10-28-8-6-26-4-2-20(23)24/h1-18H2,(H,21,22)(H,23,24)
    
    Canonical SMILES
    
    C(COCCOCCOCCOCCOCCOCCOCCOCCC(=O)O)C(=O)O

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