Bis-PEG8-acid

 CAS No.: 1246189-43-4  Cat No.: BP-501579  Purity: ≥95% 4.5  

Bis-PEG8-acid is a PEG linker containing two terminal carboxylic acid groups. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Bis-PEG8-acid

Structure of 1246189-43-4

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Category
PROTAC Linker
Molecular Formula
C20H38O12
Molecular Weight
470.51
Appearance
Pale Yellow or Colorless Oily Matter

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DMSO
Appearance
Pale Yellow or Colorless Oily Matter
ShelfLife
-20°C 3 years powder; -80°C 2 years in solvent
Storage
Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Shipping
Room temperature, or blue ice upon request.
IUPACName
3-[2-[2-[2-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Synonyms
HOOC-PEG7-CH2CH2COOH; HOOCCH2CH2O-PEG7-CH2CH2COOH; 4,7,10,13,16,19,22,25-Octaoxaoctacosanedioic acid; Bis-PEG8-COOH; 4,7,10,13,16,19,22,25-Octaoxaoctacosane-1,28-dioic Acid; Di-Acid-PEG8
Boiling Point
601.8±55.0°C (Predicted)
Density
1.179±0.06 g/cm3 (Predicted)
InChI Key
IRTAMFHIULAGCS-UHFFFAOYSA-N
InChI
InChI=1S/C20H38O12/c21-19(22)1-3-25-5-7-27-9-11-29-13-15-31-17-18-32-16-14-30-12-10-28-8-6-26-4-2-20(23)24/h1-18H2,(H,21,22)(H,23,24)
Canonical SMILES
C(COCCOCCOCCOCCOCCOCCOCCOCCC(=O)O)C(=O)O

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: Mal-PEG2-Val-Cit-amido-PAB-OH | Azido-PEG5-amine | m-PEG7-COOH | Benzyl-PEG8-azide | Amino-PEG2-t-butyl acetate | HO-PEG15-OH | Boc-Aminooxy-PEG4-CH2CO2H | N-(Azido-PEG3)-N-bis(PEG4-acid) | TCO-PEG12-acid | Bis-PEG8-acid | Azido-PEG6-acetic acid

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