Tos-PEG2-COOtBu

 CAS No.: 1309666-78-1  Cat No.: BP-501477  Purity: ≥95% 4.5  

Tos-PEG2-COOtBu linker bears a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases the solubility in aqueous media. The carboxyl group protected by tert-butyl can be deprotected under acidic conditions. Tosyl group is a very good leaving group for nucleophilic substitution reaction.

Tos-PEG2-COOtBu

Structure of 1309666-78-1

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Category
PROTAC Linker
Molecular Formula
C16H24O6S
Molecular Weight
344.42
Appearance
White Solid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DMSO
Appearance
White Solid
Storage
Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
tert-butyl 3-[2-(4-methylphenyl)sulfonyloxyethoxy]propanoate
Synonyms
tert-butyl 3-(2-(tosyloxy)ethoxy)propanoate; 2-(2-(tert-Butoxycarbonyl)ethoxy)ethyl 4-methylbenzenesulfonate; Tos-PEG2-t-butyl ester; Tos-PEG2-Boc
Boiling Point
460.6±30.0 °C at 760 mmHg
Density
1.2±0.1 g/cm3
InChI Key
OVLSSENVXOKYAD-UHFFFAOYSA-N
InChI
InChI=1S/C16H24O6S/c1-13-5-7-14(8-6-13)23(18,19)21-12-11-20-10-9-15(17)22-16(2,3)4/h5-8H,9-12H2,1-4H3
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)OCCOCCC(=O)OC(C)(C)C

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It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: N-(m-PEG9)-N'-(propargyl-PEG8)-Cy5 | Propargyl-PEG1-SS-PEG1-C2-Boc

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