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Tos-PEG2-COOtBu - CAS 1309666-78-1

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Tos-PEG2-COOtBu linker bears a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases the solubility in aqueous media. The carboxyl group protected by tert-butyl can be deprotected under acidic conditions. Tosyl group is a very good leaving group for nucleophilic substitution reaction.

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Molecular Formula
C16H24O6S
Molecular Weight
344.42

Tos-PEG2-COOtBu

    • Specification
      • Purity
        ≥95%
        Solubility
        Soluble in DMSO
        Appearance
        White Solid
        Storage
        Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        tert-butyl 3-[2-(4-methylphenyl)sulfonyloxyethoxy]propanoate
        Synonyms
        tert-butyl 3-(2-(tosyloxy)ethoxy)propanoate; 2-(2-(tert-Butoxycarbonyl)ethoxy)ethyl 4-methylbenzenesulfonate; Tos-PEG2-t-butyl ester; Tos-PEG2-Boc
    • Properties
      • Boiling Point
        460.6±30.0 °C at 760 mmHg
        Density
        1.2±0.1 g/cm3
        InChI Key
        OVLSSENVXOKYAD-UHFFFAOYSA-N
        InChI
        InChI=1S/C16H24O6S/c1-13-5-7-14(8-6-13)23(18,19)21-12-11-20-10-9-15(17)22-16(2,3)4/h5-8H,9-12H2,1-4H3
        Canonical SMILES
        CC1=CC=C(C=C1)S(=O)(=O)OCCOCCC(=O)OC(C)(C)C
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