EEF2 (Eukaryotic elongation factor 2)

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Eukaryotic elongation factor 2 (eEF2) is a protein encoded by the human gene EEF2. The protein encoded by this gene is a member of the GTP-binding translation extension factor family. EEF2 mediates the translocation step of elongation, which catalyzes the movement of tRNA from ribosomal A site to P site by GTP hydrolysis. EEF2 phosphorylates through its only known kinase eEF2K, which destroys the growth of peptides and inhibits the synthesis of general proteins. In common bacterial infections, eukaryotic extension factor 2 is the target of inhibition of diphtheria toxin and exotoxin A. eEF2 as a drug target in cancer, and in cardiovascular and neurodegenerative diseases. It is important to develop specific and potent eEF2K small molecular inhibitors for cell-based research, especially using preclinical models of the disease.

Cat.No.Product NameSourceSpeciesTagMolecular Weight
BP-800011Recombinant Human EEF2, GST-taggedE.coliHumanGST
BP-800012Recombinant Mouse EEF2 Protein (2-858 aa), His-taggedYeastMouseHis
BP-800013Recombinant Rhesus monkey EEF2 Protein, His-taggedMammalian CellsRhesus monkeyHis
BP-800014Recombinant Rat EEF2 ProteinMammalian CellsRatHis
BP-800015Recombinant Human EEF2 protein, His-taggedE. coliHumanHis
BP-800016Recombinant Human EEF2, GST-taggedWheat germHumanGST
BP-800017Recombinant Mouse EEF2 ProteinMammalian CellsMouseHis
BP-800018Recombinant Chicken EEF2Mammalian CellsChickenHis
BP-800019Recombinant Human EEF2 Protein, His-taggedE. coliHumanHis
BP-800020Recombinant Human EEF2, MYC/DDK-taggedHEK293 CellsHumanMYC/DDK
BP-800021Recombinant Human EEF2, His-taggedE. coliHumanHis

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