Azido-PEG8-NHS ester

 CAS No.: 1204834-00-3  Cat No.: BP-500155  Purity: ≥95% 4.5  

Azido-PEG8-NHS ester enables bioorthogonal click chemistry in ADC linker design, improving conjugation efficiency and stability for targeted antibody-drug conjugates with enhanced pharmacokinetics.

Azido-PEG8-NHS ester

Structure of 1204834-00-3

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Category
PROTAC Linker
Molecular Formula
C23H40N4O12
Molecular Weight
564.58
Appearance
Pale Yellow or Colorless Oily Liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DMSO (10 mm)
Appearance
Pale Yellow or Colorless Oily Liquid
ShelfLife
0-4°C for short term (days to weeks), or -20°C for long term (months).
Storage
Store at 2-8°C
Shipping
Room temperature
IUPACName
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Synonyms
Azido-PEG8-CH2CO2-NHS; N3-PEG8-C2-NHS ester; N3-PEG8-CH2CH2COONHS Ester; 1-[(1-Azido-27-oxo-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-yl)oxy]-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 1-[(27-azido-1-oxo-4,7,10,13,16,19,22,25-octaoxaheptacos-1-yl)oxy]-; 1-Azido-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid succinimidyl ester
InChI Key
AZXJVYAMFTUKFC-UHFFFAOYSA-N
InChI
InChI=1S/C23H40N4O12/c24-26-25-4-6-32-8-10-34-12-14-36-16-18-38-20-19-37-17-15-35-13-11-33-9-7-31-5-3-23(30)39-27-21(28)1-2-22(27)29/h1-20H2
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
ConcentrationVolumeMass1 mg5 mg10 mg
1 mM1.7712 mL8.8561 mL17.7123 mL
5 mM0.3542 mL1.7712 mL3.5425 mL
10 mM0.1771 mL0.8856 mL1.7712 mL

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g
Historical Records: Azido-PEG8-NHS ester

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