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Azido-PEG8-NHS ester - CAS 1204834-00-3

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Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG8-NHS ester is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

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Molecular Formula
C23H40N4O12
Molecular Weight
564.58

Azido-PEG8-NHS ester

    • Specification
      • Purity
        ≥95%
        Solubility
        Soluble in DMSO (10 mm)
        Appearance
        Pale Yellow or Colorless Oily Liquid
        Shelf Life
        0-4℃ for short term (days to weeks), or -20℃ for long term (months).
        Storage
        Store at 2-8°C
        Shipping
        Room temperature
        IUPAC Name
        (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
        Synonyms
        Azido-PEG8-CH2CO2-NHS; N3-PEG8-C2-NHS ester; N3-PEG8-CH2CH2COONHS Ester; 1-[(1-Azido-27-oxo-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-yl)oxy]-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 1-[(27-azido-1-oxo-4,7,10,13,16,19,22,25-octaoxaheptacos-1-yl)oxy]-; 1-Azido-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid succinimidyl ester
    • Properties
      • InChI Key
        AZXJVYAMFTUKFC-UHFFFAOYSA-N
        InChI
        InChI=1S/C23H40N4O12/c24-26-25-4-6-32-8-10-34-12-14-36-16-18-38-20-19-37-17-15-35-13-11-33-9-7-31-5-3-23(30)39-27-21(28)1-2-22(27)29/h1-20H2
        Canonical SMILES
        C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
    • Preparing Stock Solutions
      • ConcentrationVolumeMass1 mg5 mg10 mg
        1 mM1.7712 mL8.8561 mL17.7123 mL
        5 mM0.3542 mL1.7712 mL3.5425 mL
        10 mM0.1771 mL0.8856 mL1.7712 mL
Bio Calculators
Stock concentration: *
Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
g/mol
g
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