Pomalidomide-PEG3-NH2 hydrochloride

Pomalidomide-PEG3-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation.

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Molecular Formula
C21H26N4O8·xHCl
Molecular Weight
462.45 (free base)

Pomalidomide-PEG3-NH2 hydrochloride

    • Specification
      • Purity
        ≥98%
        Shelf Life
        2 years
        Storage
        -20°C
        Synonyms
        2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide hydrochloride
Bio Calculators
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L

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g
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