Pomalidomide-PEG3-NH2 hydrochloride

Cat No.: BP-100026

Purity: ≥98% 4.5

Pomalidomide-PEG3-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation.

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Category

E3 Ligase Ligand-Linker Conjugate

Molecular Formula

C21H26N4O8·xHCl

Molecular Weight

462.45 (free base)

* For research and manufacturing use only. Not for human or clinical use.

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Specification
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Purity

≥98%

ShelfLife

2 years

Storage

-20°C

Synonyms

2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide hydrochloride

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C₁V₁ = C₂V₂