PROTAC PLK1 Degrader-2

 Cat No.: BP-400201 4.5  

PROTAC PLK1 Degrader-2 is a N-degron pathway-based PROTAC designed to degrade Polo-like kinase 1 (PLK1), a serine/threonine protein kinase overexpressed in various tumor cells. This compound targets the Polo-box domain (PBD), which decreases cell viability, induces G2/M phase arrest, and triggers apoptosis in tumor cells.

PROTAC PLK1 Degrader-2

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Category
PROTAC
Molecular Formula
C116H216N57O23P
Molecular Weight
2808.30
Appearance
White to off-white solid

* For research and manufacturing use only. Not for human or clinical use.

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Appearance
White to off-white solid
Storage
Store at -20 °C
Sequence
RRRRRRRRRRRR-{Ahx}-PLXSX-NH2
Synonyms
H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-{Ahx}-Pro-Leu-{His(n-octylphenyl)}-Ser-{pThr}-NH2; Compound NC1

Stock concentration: *
Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
g/mol
g
Historical Records: Protac-4 | PROTAC PLK1 Degrader-2

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