Structure	Catalog	Product Name	CAS	E3 Ligase	Target	Inquiry
	BPL-201633	(2S,4R)-1-((S)-17-((S)-4-(4-Aminophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-2-(tert-butyl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2417371-03-8	VHL	BRD4	Inquiry
Molecular Weight: 983.23 Molecular Formula: C49H62N10O8S2 Density: 1.39±0.1 g/cm3 Description: It is a BRD4 degrader with antiproliferative activity in vitro and antitumor efficacy in vivo.
	BPL-201634	(2S,4R)-1-((S)-17-((S)-4-(4-(3-Aminoprop-1-yn-1-yl)phenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-2-(tert-butyl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide		VHL	BRD4	Inquiry
Molecular Weight: 1021.28 Molecular Formula: C52H64N10O8S2 Description: It is a BRD4 degrader with antiproliferative activity in vitro and antitumor efficacy in vivo.
	BPL-201635	(2S,4R)-1-((S)-2-(tert-Butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecanoyl)-4-hydroxy-N-(2-(2-(methylamino)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2417371-21-0	VHL	BRD4	Inquiry
Molecular Weight: 1075.76 Molecular Formula: C52H67ClN10O9S2 Density: 1.38±0.1 g/cm3 Description: It is a BRD4 degrader with antiproliferative activity in vitro and antitumor efficacy in vivo.
	BPL-201636	(2S,4R)-1-((S)-2-(tert-Butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)-2-(piperidin-4-yloxy)benzyl)pyrrolidine-2-carboxamide	2417371-25-4	VHL	BRD4	Inquiry
Molecular Weight: 1101.79 Molecular Formula: C54H69ClN10O9S2 Density: 1.41±0.1 g/cm3 Description: It is a BRD4 degrader with antiproliferative activity in vitro and antitumor efficacy in vivo.
	BPL-201637	(2S,4R)-1-((S)-2-(2-(3-Amino-5-(2-(2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamido)ethoxy)phenethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2417370-95-5	VHL	BRD4	Inquiry
Molecular Weight: 1049.72 Molecular Formula: C53H61ClN10O7S2 Density: 1.41±0.1 g/cm3 Description: It is a BRD4 degrader with antiproliferative activity in vitro and antitumor efficacy in vivo.
	BPL-201638	(2S,4R)-1-((S)-2-(2-(((3S,5R)-5-((2-(2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamido)ethoxy)methyl)piperidin-3-yl)methoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide		VHL	BRD4	Inquiry
Molecular Weight: 1041.74 Molecular Formula: C52H65ClN10O7S2 Density: 1.41±0.1 g/cm3 Description: It is a BRD4 degrader with antiproliferative activity in vitro and antitumor efficacy in vivo.
	BPL-201639	(2S,4R)-1-((S)-2-(3-(3-Amino-5-(2-(2-((3-(4-((S)-2,3,9-trimethyl-6-(thiazol-2-ylmethyl)-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)phenyl)prop-2-yn-1-yl)oxy)ethoxy)ethyl)phenyl)propanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide		VHL	BRD4	Inquiry
Molecular Weight: 1107.44 Molecular Formula: C59H66N10O6S3 Description: It is a BRD4 degrader with antiproliferative activity in vitro and antitumor efficacy in vivo.
	BPL-201640	2-(2-((S)-4-(4-(3-(2-(3-Amino-5-(3-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-3-oxopropyl)phenethoxy)ethoxy)prop-1-yn-1-yl)phenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamido)ethane-1-sulfonic acid	2417371-41-4	VHL	BRD4	Inquiry
Molecular Weight: 1175.47 Molecular Formula: C59H70N10O10S3 Density: 1.38±0.1 g/cm3 Description: It is a BRD4 degrader with antiproliferative activity in vitro and antitumor efficacy in vivo.
	BPL-201641	(2S,4R)-1-((S)-2-(2-((6-(2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamido)hexa-2,4-diyn-1-yl)oxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2417371-31-2	VHL	BRD4	Inquiry
Molecular Weight: 962.60 Molecular Formula: C49H52ClN9O6S2 Density: 1.36±0.1 g/cm3 Description: It is a BRD4 degrader with antiproliferative activity in vitro and antitumor efficacy in vivo.
	BPL-201642	N-(2-(4-((2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)amino)-3,3-dimethyl-4-oxobutyl)-5-ethoxy-1-methyl-1H-benzo[d]imidazol-6-yl)-6-(trifluoromethyl)picolinamide	2713973-43-2	CRBN	IRAK4	Inquiry
Molecular Weight: 776.77 Molecular Formula: C38H39F3N8O7 Boiling Point: 951.1±65.0°C at 760 Torr Density: 1.47±0.1 g/cm3 Description: It is a potent IRAK4 degrader that can effectively inhibit the activation of the downstream NF-κB signaling pathway.
	BPL-201643	N-(2-(4-((3-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)propyl)amino)-3,3-dimethyl-4-oxobutyl)-5-ethoxy-1-methyl-1H-benzo[d]imidazol-6-yl)-6-(trifluoromethyl)picolinamide	2713973-44-3	CRBN	IRAK4	Inquiry
Molecular Weight: 790.79 Molecular Formula: C39H41F3N8O7 Boiling Point: 957.7±65.0°C at 760 Torr Density: 1.45±0.1 g/cm3 Description: It is a potent IRAK4 degrader that can effectively inhibit the activation of the downstream NF-κB signaling pathway.
	BPL-201644	N-(2-(4-((4-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)amino)-3,3-dimethyl-4-oxobutyl)-5-ethoxy-1-methyl-1H-benzo[d]imidazol-6-yl)-6-(trifluoromethyl)picolinamide	2713973-45-4	CRBN	IRAK4	Inquiry
Molecular Weight: 804.83 Molecular Formula: C40H43F3N8O7 Boiling Point: 964.6±65.0°C at 760 Torr Density: 1.43±0.1 g/cm3 Description: It is a potent IRAK4 degrader that can effectively inhibit the activation of the downstream NF-κB signaling pathway.
	BPL-201645	N-(2-(4-((5-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)pentyl)amino)-3,3-dimethyl-4-oxobutyl)-5-ethoxy-1-methyl-1H-benzo[d]imidazol-6-yl)-6-(trifluoromethyl)picolinamide	2713973-46-5	CRBN	IRAK4	Inquiry
Molecular Weight: 818.85 Molecular Formula: C41H45F3N8O7 Boiling Point: 969.0±65.0°C at 760 Torr Density: 1.42±0.1 g/cm3 Description: It is a potent IRAK4 degrader that can effectively inhibit the activation of the downstream NF-κB signaling pathway.
	BPL-201646	N-(2-(4-((6-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)hexyl)amino)-3,3-dimethyl-4-oxobutyl)-5-ethoxy-1-methyl-1H-benzo[d]imidazol-6-yl)-6-(trifluoromethyl)picolinamide	2713973-47-6	CRBN	IRAK4	Inquiry
Molecular Weight: 832.88 Molecular Formula: C42H47F3N8O7 Boiling Point: 973.6±65.0°C at 760 Torr Density: 1.40±0.1 g/cm3 Description: It is a potent IRAK4 degrader that can effectively inhibit the activation of the downstream NF-κB signaling pathway.
	BPL-201647	N-(2-(4-((7-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)heptyl)amino)-3,3-dimethyl-4-oxobutyl)-5-ethoxy-1-methyl-1H-benzo[d]imidazol-6-yl)-6-(trifluoromethyl)picolinamide	2713973-48-7	CRBN	IRAK4	Inquiry
Molecular Weight: 846.91 Molecular Formula: C43H49F3N8O7 Boiling Point: 978.4±65.0°C at 760 Torr Density: 1.39±0.1 g/cm3 Description: It is a potent IRAK4 degrader that can effectively inhibit the activation of the downstream NF-κB signaling pathway.
	BPL-201648	N-(2-(4-((2-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethyl)amino)-3,3-dimethyl-4-oxobutyl)-5-ethoxy-1-methyl-1H-benzo[d]imidazol-6-yl)-6-(trifluoromethyl)picolinamide	2713973-49-8	CRBN	IRAK4	Inquiry
Molecular Weight: 820.83 Molecular Formula: C40H43F3N8O8 Boiling Point: 973.9±65.0°C at 760 Torr Density: 1.45±0.1 g/cm3 Description: It is a potent IRAK4 degrader that can effectively inhibit the activation of the downstream NF-κB signaling pathway.
	BPL-201649	N-(2-(4-((2-(2-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethyl)amino)-3,3-dimethyl-4-oxobutyl)-5-ethoxy-1-methyl-1H-benzo[d]imidazol-6-yl)-6-(trifluoromethyl)picolinamide	2713973-50-1	CRBN	IRAK4	Inquiry
Molecular Weight: 864.88 Molecular Formula: C42H47F3N8O9 Boiling Point: 994.9±65.0°C at 760 Torr Density: 1.43±0.1 g/cm3 Description: It is a potent IRAK4 degrader that can effectively inhibit the activation of the downstream NF-κB signaling pathway.
	BPL-201650	FC-1	2271036-26-9	CRBN	FAK	Inquiry
Molecular Weight: 920.89 Molecular Formula: C39H39F3N14O8S Density: 1.62±0.1 g/cm3 Description: It is a FAK-targeting PROTAC that exhibits rapid and reversible FAK degradation in various cell lines in vitro.
	BPL-201651	FC-2	2271036-28-1	CRBN	FAK	Inquiry
Molecular Weight: 964.95 Molecular Formula: C41H43F3N14O9S Density: 1.59±0.1 g/cm3 Description: It is a FAK-targeting PROTAC that exhibits rapid and reversible FAK degradation in various cell lines in vitro.
	BPL-201652	FC-3	2271036-29-2	CRBN	FAK	Inquiry
Molecular Weight: 1008.98 Molecular Formula: C43H47F3N14O10S Density: 1.56±0.1 g/cm3 Description: It is a FAK-targeting PROTAC that exhibits rapid and reversible FAK degradation in various cell lines in vitro.

PROTAC Library