Structure	Catalog	Product Name	CAS	E3 Ligase	Target	Inquiry
	BPL-201553	N-(2-(2-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethyl)-12-(4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-12-oxododecanamide	2523017-01-6	CRBN	PARP1	Inquiry
Molecular Weight: 965.09 Molecular Formula: C51H61FN8O10 Density: 1.37±0.1 g/cm3 Description: It is a highly potent and efficacious proteolysis-targeting chimera degrader of PARP1 for cancers treatment.
	BPL-201554	N-(3-(2-(2-(3-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)propoxy)ethoxy)ethoxy)propyl)-12-(4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-12-oxododecanamide	2523017-02-7	CRBN	PARP1	Inquiry
Molecular Weight: 1037.18 Molecular Formula: C55H69FN8O11 Density: 1.34±0.1 g/cm3 Description: It is a highly potent and efficacious proteolysis-targeting chimera degrader of PARP1 for cancers treatment.
	BPL-201555	N-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)ethyl)-12-(4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-12-oxododecanamide	2631575-42-1	CRBN	PARP1	Inquiry
Molecular Weight: 876.99 Molecular Formula: C47H53FN8O8 Density: 1.40±0.1 g/cm3 Description: It is a highly potent and efficacious proteolysis-targeting chimera degrader of PARP1 for cancers treatment.
	BPL-201556	N-(2-((2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)amino)ethyl)-12-(4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-12-oxododecanamide	2523017-03-8	CRBN	PARP1	Inquiry
Molecular Weight: 862.99 Molecular Formula: C47H55FN8O7 Density: 1.37±0.1 g/cm3 Description: It is a highly potent and efficacious proteolysis-targeting chimera degrader of PARP1 for cancers treatment.
	BPL-201557	(2S,4R)-1-((S)-2-(12-(4-(2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-12-oxododecanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2523016-07-9	VHL	PARP1	Inquiry
Molecular Weight: 991.24 Molecular Formula: C54H67FN8O7S Density: 1.31±0.1 g/cm3 Description: It is a highly potent and efficacious proteolysis-targeting chimera degrader of PARP1 for cancers treatment.
	BPL-201558	(2S,4R)-1-((S)-2-(2-(12-(4-(2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-12-oxododecanamido)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2523016-36-4	VHL	PARP1	Inquiry
Molecular Weight: 1048.28 Molecular Formula: C56H70FN9O8S Density: 1.32±0.1 g/cm3 Description: It is a highly potent and efficacious proteolysis-targeting chimera degrader of PARP1 for cancers treatment.
	BPL-201559	(2S,4R)-1-((S)-2-(4-(12-(4-(2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-12-oxododecanamido)butanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2523016-34-2	VHL	PARP1	Inquiry
Molecular Weight: 1076.35 Molecular Formula: C58H74FN9O8S Density: 1.31±0.1 g/cm3 Description: It is a highly potent and efficacious proteolysis-targeting chimera degrader of PARP1 for cancers treatment.
	BPL-201560	(2S,4R)-1-((S)-2-(6-(12-(4-(2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-12-oxododecanamido)hexanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2523016-32-0	VHL	PARP1	Inquiry
Molecular Weight: 1104.38 Molecular Formula: C60H78FN9O8S Density: 1.29±0.1 g/cm3 Description: It is a highly potent and efficacious proteolysis-targeting chimera degrader of PARP1 for cancers treatment.
	BPL-201561	2-(2,6-Dioxopiperidin-3-yl)-4-((2-(4-(6-(6-((R)-2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazin-3-yl)pyridin-2-yl)piperazin-1-yl)-2-oxoethyl)amino)isoindoline-1,3-dione	2412055-89-9	CRBN	TRKA	Inquiry
Molecular Weight: 756.79 Molecular Formula: C40H37FN10O5 Density: 1.56±0.1 g/cm3 Description: It is a first-in-class potent and selective tropomyosin receptor kinase degrader.
	BPL-201562	2-(2,6-Dioxopiperidin-3-yl)-4-((3-(4-(6-(6-((R)-2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazin-3-yl)pyridin-2-yl)piperazin-1-yl)-3-oxopropyl)amino)isoindoline-1,3-dione	2412055-92-4	CRBN	TRKA	Inquiry
Molecular Weight: 770.83 Molecular Formula: C41H39FN10O5 Density: 1.53±0.1 g/cm3 Description: It is a first-in-class potent and selective tropomyosin receptor kinase degrader.
	BPL-201563	2-(2,6-Dioxopiperidin-3-yl)-4-((4-(4-(6-(6-((R)-2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazin-3-yl)pyridin-2-yl)piperazin-1-yl)-4-oxobutyl)amino)isoindoline-1,3-dione	2412055-79-7	CRBN	TRKA	Inquiry
Molecular Weight: 784.85 Molecular Formula: C42H41FN10O5 Density: 1.51±0.1 g/cm3 Description: It is a first-in-class potent and selective tropomyosin receptor kinase degrader.
	BPL-201564	2-(2,6-Dioxopiperidin-3-yl)-4-((5-(4-(6-(6-((R)-2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazin-3-yl)pyridin-2-yl)piperazin-1-yl)-5-oxopentyl)amino)isoindoline-1,3-dione	2412055-80-0	CRBN	TRKA	Inquiry
Molecular Weight: 798.88 Molecular Formula: C43H43FN10O5 Density: 1.49±0.1 g/cm3 Description: It is a first-in-class potent and selective tropomyosin receptor kinase degrader.
	BPL-201565	CG416	2412055-81-1	CRBN	TRKA TRKB TRKC	Inquiry
Molecular Weight: 812.91 Molecular Formula: C44H45FN10O5 Density: 1.48±0.1 g/cm3 Description: It is a first-in-class potent and selective tropomyosin receptor kinase degrader.
	BPL-201566	2-(2,6-Dioxopiperidin-3-yl)-4-((7-(4-(6-(6-((R)-2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazin-3-yl)pyridin-2-yl)piperazin-1-yl)-7-oxoheptyl)amino)isoindoline-1,3-dione	2412055-75-3	CRBN	TRKA	Inquiry
Molecular Weight: 826.93 Molecular Formula: C45H47FN10O5 Density: 1.46±0.1 g/cm3 Description: It is a first-in-class potent and selective tropomyosin receptor kinase degrader.
	BPL-201567	2-(2,6-Dioxopiperidin-3-yl)-4-((8-(4-(6-(6-((R)-2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazin-3-yl)pyridin-2-yl)piperazin-1-yl)-8-oxooctyl)amino)isoindoline-1,3-dione	2412055-90-2	CRBN	TRKA	Inquiry
Molecular Weight: 840.96 Molecular Formula: C46H49FN10O5 Density: 1.44±0.1 g/cm3 Description: It is a first-in-class potent and selective tropomyosin receptor kinase degrader.
	BPL-201568	CG428	2412055-93-5	CRBN	TRKA TRKB TRKC	Inquiry
Molecular Weight: 814.88 Molecular Formula: C43H43FN10O6 Density: 1.51±0.1 g/cm3 Description: It is a first-in-class potent and selective tropomyosin receptor kinase degrader.
	BPL-201569	2-(2,6-Dioxopiperidin-3-yl)-4-((2-(2-(3-(4-(6-(6-((R)-2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazin-3-yl)pyridin-2-yl)piperazin-1-yl)-3-oxopropoxy)ethoxy)ethyl)amino)isoindoline-1,3-dione	2412055-94-6	CRBN	TRKA	Inquiry
Molecular Weight: 858.93 Molecular Formula: C45H47FN10O7 Density: 1.48±0.1 g/cm3 Description: It is a first-in-class potent and selective tropomyosin receptor kinase degrader.
	BPL-201570	2-(2,6-Dioxopiperidin-3-yl)-4-((2-(2-(2-(3-(4-(6-(6-((R)-2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazin-3-yl)pyridin-2-yl)piperazin-1-yl)-3-oxopropoxy)ethoxy)ethoxy)ethyl)amino)isoindoline-1,3-dione	2412055-76-4	CRBN	TRKA	Inquiry
Molecular Weight: 902.99 Molecular Formula: C47H51FN10O8 Density: 1.46±0.1 g/cm3 Description: It is a first-in-class potent and selective tropomyosin receptor kinase degrader.
	BPL-201571	2-(2,6-Dioxopiperidin-3-yl)-4-((15-(4-(6-(6-((R)-2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazin-3-yl)pyridin-2-yl)piperazin-1-yl)-15-oxo-3,6,9,12-tetraoxapentadecyl)amino)isoindoline-1,3-dione	2412059-52-8	CRBN	TRKA	Inquiry
Molecular Weight: 947.04 Molecular Formula: C49H55FN10O9 Density: 1.44±0.1 g/cm3 Description: It is a first-in-class potent and selective tropomyosin receptor kinase degrader.
	BPL-201572	(2S,4R)-1-((S)-11-(tert-Butyl)-1-(3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)phenyl)-1,9-dioxo-3-oxa-2,7,10-triazadodecan-12-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2756322-89-9	VHL	MEK1 MEK2	Inquiry
Molecular Weight: 935.81 Molecular Formula: C40H45F3IN7O6S Density: 1.488±0.06 g/cm3 Description: It is a potent and selective mitogen-activated protein kinase kinase 1/2 (MEK1/2) heterobifunctional small-molecule degrader.

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