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ALV1 - CAS 2438124-79-7

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ALV1 effectively induces the degradation of Ikaros and Helios without unexpected off-target effects. ALV1 binds to CRBN with an IC50 of 0.55 µM. It efficiently degrades cells expressing IKZF1Δ and IKZF2Δ GFP fusions, with DC50 values of 2.5 and 10.3 nM, respectively.

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Molecular Formula
C25H23ClN4O5
Molecular Weight
494.93

ALV1

    • Specification
      • Solubility
        DMSO: 50 mg/mL (101.02 mM; Need ultrasonic)
        Appearance
        Solid
        Storage
        Store at -20°C
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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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