Azido-PEG3-acetic acid

Name: Azido-PEG3-acetic acid
Brand: BOC Sciences
Price: 899 USD
Availability: MadeToOrder

CAS No.: 172531-37-2

Cat No.: BP-500011

Purity: 95% 4.5

N3-PEG3-CH2COOH is a PROTAC linker, which refers to the alkyl/ether composition. N3-PEG3-CH2COOH can be used in the synthesis of a series of PROTACs. N3-PEG3-CH2COOH is a PEG derivative containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Structure of 172531-37-2

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Category

PROTAC Linker

Molecular Formula

C8H15N3O5

Molecular Weight

233.22

Appearance

Light Yellow to Brown Clear Liquid

* For research and manufacturing use only. Not for human or clinical use.

Size	Price	Stock	Quantity
5 g	$899	In stock

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Purity

95%

Solubility

Soluble in DCM, DMF, DMSO, Water

Appearance

Light Yellow to Brown Clear Liquid

Storage

Store at 2-8 °C

Shipping

Room temperature in continental US; may vary elsewhere

IUPACName

2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetic acid

Synonyms

Azido-PEG3-CH2CO2H; 11-Azido-3,6,9-trioxaundecanoic Acid; N3-PEG3-CH2COOH; {2-[2-(2-Azidoethoxy)ethoxy]ethoxy}acetic acid; Acetic acid, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-; Azido-PEG3-CH2COOH; N3-AEEEA; Azido-PEG3-propionic acid

InChI Key

GIXBCECBLAEYKA-UHFFFAOYSA-N

InChI

InChI=1S/C8H15N3O5/c9-11-10-1-2-14-3-4-15-5-6-16-7-8(12)13/h1-7H2,(H,12,13)

Canonical SMILES

C(COCCOCCOCC(=O)O)N=[N+]=[N-]

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C₁V₁ = C₂V₂