m-PEG10-COOH

 CAS No.: 2409969-94-2  Cat No.: BP-500434  Purity: >98% 4.5  

m-PEG10-COOH is a hydrophilic PEG-based ADC linker intermediate featuring a 10-unit PEG spacer and carboxyl terminal. It enhances antibody solubility, improves conjugation efficiency, and provides stability for controlled drug release in antibody-drug conjugate development and targeted cancer therapy.

m-PEG10-COOH

Structure of 2409969-94-2

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Category
PROTAC Linker
Molecular Formula
C22H44O12
Molecular Weight
500.58
Appearance
Pale Yellow or Colorless Oily Liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
>98%
Solubility
10 mm in DMSO
Appearance
Pale Yellow or Colorless Oily Liquid
ShelfLife
0-4°C for short term (days to weeks), or -20°C for long term (months).
Storage
Store at 2-8°C
Shipping
Room temperature
IUPACName
3-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Synonyms
m-PEG10-acid; mPEG9-propionic acid; mPEG9-CH2CH2COOH; mPEG10-acid; 2,5,8,11,14,17,20,23,26,29-Decaoxadotriacontan-32-oic acid
Boiling Point
568.3±50.0°C at 760 mmHg
Density
1.1±0.1 g/cm3
InChI Key
DWDMPMQTMMOYQC-UHFFFAOYSA-N
InChI
InChI=1S/C22H44O12/c1-25-4-5-27-8-9-29-12-13-31-16-17-33-20-21-34-19-18-32-15-14-30-11-10-28-7-6-26-3-2-22(23)24/h2-21H2,1H3,(H,23,24)
Canonical SMILES
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Historical Records: 3,6,9,12,15-Pentaoxaoctadec-17-yn-1-ol mesylate | t-Boc-N-amido-PEG6-Tos | Tetraethylene glycol monohexadecyl ether | Diethylene Glycol Bis(2-propynyl) Ether | t-Boc-N-amido-PEG6-propionic acid | Tos-PEG5-t-butyl ester | m-PEG2-O-Ph-3-NH2 | m-PEG12-DBCO | THP-PEG11-THP | m-PEG8-DBCO | m-PEG10-COOH

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