TCO-PEG4-DBCO

 CAS No.: 1801863-88-6  Cat No.: BP-501395  Purity: >98.0% 4.5  

TCO-PEG4-DBCO is a dual-functional ADC linker combining trans-cyclooctene and DBCO groups for click chemistry and bioorthogonal reactions. Used in pretargeting strategies, it supports rapid, selective antibody-payload assembly in drug conjugate synthesis.

TCO-PEG4-DBCO

Structure of 1801863-88-6

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Category
PROTAC Linker
Molecular Formula
C38H49N3O8
Molecular Weight
675.81
Appearance
Solid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
>98.0%
Solubility
10 mm in DMSO
Appearance
Solid
ShelfLife
≥ 2 years
Storage
Store at -5°C,keep in dry and avoid sunlight.
Shipping
Room temperature, or blue ice upon request.
IUPACName
Synonyms
(4E)-Tco-peg4-dbco
InChI Key
MXNJAXPSMJDOOY-UHFFFAOYSA-N
InChI
InChI=1S/C38H49N3O8/c42-36(39-20-18-37(43)41-30-33-12-7-6-10-31(33)16-17-32-11-8-9-15-35(32)41)19-22-45-24-26-47-28-29-48-27-25-46-23-21-40-38(44)49-34-13-4-2-1-3-5-14-34/h1-2,6-12,15,34H,3-5,13-14,18-30H2,(H,39,42)(H,40,44)
Canonical SMILES
C1CC=CCCC(C1)OC(=O)NCCOCCOCCOCCOCCC(=O)NCCC(=O)N2CC3=CC=CC=C3C#CC4=CC=CC=C42

Stock concentration: *
Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

Calculate
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
g/mol
g
Historical Records: PEG20-Tos | N-(Azido-PEG2)-N-Boc-PEG3-Boc | endo-BCN-PEG2-PFP ester | 1-Isothiocyanato-PEG3-azide | N,N'-DME-N-PEG2-Boc | 2-Propenoic acid,2-[2-(2-hydroxyethoxy)ethoxy]ethyl ester | 2-[2-(Prop-2-yn-1-yloxy)ethoxy]acetic acid | Tos-PEG3-t-butyl ester | Tos-PEG3-C2-methyl ester | N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 | TCO-PEG4-DBCO

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