BSJ-4-116 - CAS 2519823-34-6

BSJ-4-116 is a PROTAC linked to ligands for Cereblon and CDK. It's a potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. It downregulates DDR genes by prematurely terminating transcription, particularly by increasing poly(adenylation). It exhibits strong antiproliferative effects, both alone and in combination with the poly(ADP-ribose) polymerase inhibitor Olaparib.

* Please be kindly noted that our services and products can only be used for research to organizations or companies and not intended for any clinical or individuals.

Molecular Formula
C40H49ClN8O8S
Molecular Weight
837.38

BSJ-4-116

    • Specification
      • Solubility
        DMSO: 250 mg/mL (298.55 mM; Need ultrasonic)
        Appearance
        Solid
        Storage
        Store at -20°C
Bio Calculators
Stock concentration: *
Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g
Related Products
BOC Sciences Support

Please contact us with any specific requirements and we will get back to you as soon as possible.


  • Verification code

We invite you to contact us at or through our contact form above for more information about our services and products.

USA
  • International:
  • US & Canada (Toll free):
  • Email:
  • Fax:
UK
  • Email:
Inquiry Basket