N-Succinimidyl 3-(Bromoacetamido)propionate

 CAS No.: 57159-62-3  Cat No.: BP-501409  Purity: >99.3% 4.5  

N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-Succinimidyl 3-(Bromoacetamido)propionate is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

N-Succinimidyl 3-(Bromoacetamido)propionate

Structure of 57159-62-3

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Category
PROTAC Linker
Molecular Formula
C9H11BrN2O5
Molecular Weight
307.10
Appearance
Off-white to white waxy solid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
>99.3%
Solubility
10 mm in DMSO
Appearance
Off-white to white waxy solid
ShelfLife
-20°C 3 years powder; -80°C 2 years in solvent
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Shipping
Room temperature
IUPACName
(2,5-dioxopyrrolidin-1-yl) 3-[(2-bromoacetyl)amino]propanoate
Synonyms
2,5-Dioxopyrrolidin-1-yl 3-(2-bromoacetamido)propanoate; Succinimidyl-3-(bromoacetamido)propionate; 3-(2-bromoacetamido)propanoic acid NHS ester
Melting Point
93-94°C
Density
1.69 g/cm3
InChI Key
WGMMKWFUXPMTRW-UHFFFAOYSA-N
InChI
InChI=1S/C9H11BrN2O5/c10-5-6(13)11-4-3-9(16)17-12-7(14)1-2-8(12)15/h1-5H2,(H,11,13)
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)CCNC(=O)CBr

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: N-(Azido-PEG3)-N-bis(PEG3-Boc) | t-Boc-Aminooxy-PEG3-azide | Methyltetrazine-PEG5-alkyne | N-(Boc-PEG3)-N-bis(PEG2-alcohol) | DBCO-NH-Boc | S-acetyl-PEG6-Tos | PEG2-ethyl acetate | N-Me-N-bis-PEG3 | Tetraethyl decamethylenediphosphonate, 98% | Benzyl-PEG2-CH2COOH | N-Succinimidyl 3-(Bromoacetamido)propionate

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