N-Succinimidyl 3-(Bromoacetamido)propionate - CAS 57159-62-3

N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-Succinimidyl 3-(Bromoacetamido)propionate is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

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Molecular Formula
C9H11BrN2O5
Molecular Weight
307.10

N-Succinimidyl 3-(Bromoacetamido)propionate

    • Specification
      • Purity
        >99.3%
        Solubility
        10 mm in DMSO
        Appearance
        Off-white to white waxy solid
        Shelf Life
        -20°C 3 years powder; -80°C 2 years in solvent
        Storage
        Store at -20 °C, keep in dry and avoid sunlight.
        Shipping
        Room temperature
        IUPAC Name
        (2,5-dioxopyrrolidin-1-yl) 3-[(2-bromoacetyl)amino]propanoate
        Synonyms
        2,5-Dioxopyrrolidin-1-yl 3-(2-bromoacetamido)propanoate; Succinimidyl-3-(bromoacetamido)propionate; 3-(2-bromoacetamido)propanoic acid NHS ester
    • Properties
      • Melting Point
        93-94°C
        Density
        1.69 g/cm3
        InChI Key
        WGMMKWFUXPMTRW-UHFFFAOYSA-N
        InChI
        InChI=1S/C9H11BrN2O5/c10-5-6(13)11-4-3-9(16)17-12-7(14)1-2-8(12)15/h1-5H2,(H,11,13)
        Canonical SMILES
        C1CC(=O)N(C1=O)OC(=O)CCNC(=O)CBr
Bio Calculators
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It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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