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Pomalidomide-PEG6-NH2 hydrochloride - CAS 2341841-01-6

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Pomalidomide-PEG6-NH2 hydrochloride is a synthetic E3 ligase ligand-linker conjugate containing a cereblon ligand based on Pomalidomide and a PEG linker of 6 O(CH2)2 units with terminal amine, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand.

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Molecular Formula
C₂₅H₃₆ClN₃O₁₀
Molecular Weight
574.02

Pomalidomide-PEG6-NH2 hydrochloride

    • Specification
      • Purity
        ≥95% by HPLC
        Storage
        Store at -20°C
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        4-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride
        Synonyms
        Thalidomide - linker 12
    • Properties
      • InChI
        1S/C25H35N3O10.ClH/c26-6-7-33-8-9-34-10-11-35-12-13-36-14-15-37-16-17-38-20-3-1-2-18-22(20)25(32)28(24(18)31)19-4-5-21(29)27-23(19)30;/h1-3,19H,4-17,26H2,(H,27,29,30);1H
        Canonical SMILES
        O=C(C1=C(C(OCCOCCOCCOCCOCCOCCN)=CC=C1)C2=O)N2C(C(N3)=O)CCC3=O.Cl
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