t-Boc-N-amido-PEG1-bromide

 CAS No.: 164332-88-1  Cat No.: BP-500656  Purity: >98.0% 4.5  

t-Boc-N-amido-PEG1-bromide is a PEG linker containing a bromide group and a Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.

t-Boc-N-amido-PEG1-bromide

Structure of 164332-88-1

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Category
PROTAC Linker
Molecular Formula
C9H18BrNO3
Molecular Weight
268.15
Appearance
Pale Yellow or Colorless Oily Liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
>98.0%
Solubility
Soluble in DCM, DMF, DMSO, Water
Appearance
Pale Yellow or Colorless Oily Liquid
ShelfLife
0-4°C for short term (days to weeks), or -20°C for long term (months).
Storage
Store at 2-8°C, keep in dry and avoid sunlight
Shipping
Room temperature, or blue ice upon request.
IUPACName
tert-butyl N-[2-(2-bromoethoxy)ethyl]carbamate
Synonyms
Br-PEG1-NHBoc; tert-Butyl (2-(2-bromoethoxy)ethyl)carbamate; Boc-NH-PEG1-Br; N-Boc-2-(2-bromoethoxy)ethanamine; BocNH-PEG1-CH2CH2Br; Carbamic acid, N-[2-(2-bromoethoxy)ethyl]-, 1,1-dimethylethyl ester; N-Boc-PEG1-bromide; 2-Methyl-2-propanyl [2-(2-bromoethoxy)ethyl]carbamate
Boiling Point
336.6±0.0 °C at 760 mmHg
Density
1.283±0.06 g/cm3 (Predicted)
InChI Key
DMOPZPBTLCZSGL-UHFFFAOYSA-N
InChI
InChI=1S/C9H18BrNO3/c1-9(2,3)14-8(12)11-5-7-13-6-4-10/h4-7H2,1-3H3,(H,11,12)
Canonical SMILES
CC(C)(C)OC(=O)NCCOCCBr

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Historical Records: Active-mono-sulfone-PEG8-acid | Lipoamido-PEG4-acid | Aminooxy-PEG4-Aminooxy | Bromo-PEG2-phosphonic acid ethyl ester | t-Boc-N-amido-PEG1-bromide

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