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Bis-PEG2-acid - CAS 19364-66-0

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Bis-PEG2-acid is a PEG linker containing two terminal carboxylic acid groups. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

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Molecular Formula
C8H14O6
Molecular Weight
206.19

Bis-PEG2-acid

    • Specification
      • Related CAS
        51178-68-8 (polymer)
        Purity
        ≥95%
        Solubility
        Soluble in DMF, DMSO, Water
        Appearance
        Pale Yellow or Colorless Oily Matter
        Storage
        Store at 2-8°C
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        3-[2-(2-carboxyethoxy)ethoxy]propanoic acid
        Synonyms
        Propanoic acid, 3,3'-[1,2-ethanediylbis(oxy)]bis-; 3,3'-(Ethane-1,2-diylbis(oxy))dipropionic acid; 3,3'-(Ethylenedioxy)dipropionic acid; HOOCCH2CH2O-PEG1-CH2CH2COOH; Bis-PEG2-COOH; 1,2-Bis(2-carboxyethoxy)ethane
    • Properties
      • Boiling Point
        407.1±35.0°C (Predicted)
        Melting Point
        66°C
        Density
        1.0869 g/cm3
        InChI Key
        BOXWYBCUJGWEOJ-UHFFFAOYSA-N
        InChI
        InChI=1S/C8H14O6/c9-7(10)1-3-13-5-6-14-4-2-8(11)12/h1-6H2,(H,9,10)(H,11,12)
        Canonical SMILES
        C(COCCOCCC(=O)O)C(=O)O
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