Bis-PEG2-acid

 CAS No.: 19364-66-0  Cat No.: BP-500666  Purity: ≥95% 4.5  

Bis-PEG2-acid is a PEG linker containing two terminal carboxylic acid groups. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Bis-PEG2-acid

Structure of 19364-66-0

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Category
PROTAC Linker
Molecular Formula
C8H14O6
Molecular Weight
206.19
Appearance
Pale Yellow or Colorless Oily Matter

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DMF, DMSO, Water
Appearance
Pale Yellow or Colorless Oily Matter
Storage
Store at 2-8°C
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
3-[2-(2-carboxyethoxy)ethoxy]propanoic acid
Synonyms
Propanoic acid, 3,3'-[1,2-ethanediylbis(oxy)]bis-; 3,3'-(Ethane-1,2-diylbis(oxy))dipropionic acid; 3,3'-(Ethylenedioxy)dipropionic acid; HOOCCH2CH2O-PEG1-CH2CH2COOH; Bis-PEG2-COOH; 1,2-Bis(2-carboxyethoxy)ethane
Boiling Point
407.1±35.0°C (Predicted)
Melting Point
66°C
Density
1.0869 g/cm3
InChI Key
BOXWYBCUJGWEOJ-UHFFFAOYSA-N
InChI
InChI=1S/C8H14O6/c9-7(10)1-3-13-5-6-14-4-2-8(11)12/h1-6H2,(H,9,10)(H,11,12)
Canonical SMILES
C(COCCOCCC(=O)O)C(=O)O

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It is commonly abbreviated as: C1V1 = C2V2

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Historical Records: OTs-C6-OBn | Mal-PEG5-NHS ester | Bis-PEG4-PFP ester | m-PEG10-Tos | SPDP-PEG4-NHS ester | Mal-PEG4-alcohol | Thiol-PEG3-alcohol | Bis-PEG5-PFP ester | F-PEG2-COOH | Br-PEG6-acid | Bis-PEG2-acid

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