Tetrazine-Amine

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Tetrazine-Amine

CAS No.: 1092689-33-2

Cat No.: BP-502178 4.5

Tetrazine-Amine engages in rapid and highly selective cycloadditions with strained alkenes-trans-cyclooctene, norbornene, and cyclopropene-generating robust dihydropyridazine linkers. The exceptional reaction rate and chemoselectivity allow two scarce biopolymers to be covalently joined in water and amid a multitude of competing functionalities. Operating with complete orthogonality to native biology, this process proceeds efficiently inside even live organisms without perturbing cellular chemistry. Consequently, tetrazine-TCO coupling has become a versatile platform for fluorescence imaging, targeted drug delivery, PET and SPECT diagnostics, radionuclide therapy, radiochemistry, and drug-target discovery.

Structure of 1092689-33-2

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Molecular Formula

C9H9N5

Molecular Weight

187.20

* For research and manufacturing use only. Not for human or clinical use.

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IUPACName

[4-(1,2,4,5-tetrazin-3-yl)phenyl]methanamine

Boiling Point

403.4±47.0 °C at 760 mmHg

Density

1.3±0.1 g/cm3

InChI Key

JGCOJRPYFRRONJ-UHFFFAOYSA-N

InChI

InChI=1S/C9H9N5/c10-5-7-1-3-8(4-2-7)9-13-11-6-12-14-9/h1-4,6H,5,10H2

Canonical SMILES

C1=CC(=CC=C1CN)C2=NN=CN=N2

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It is commonly abbreviated as: C₁V₁ = C₂V₂

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