Tos-PEG4-acid

 CAS No.: 1453117-42-4  Cat No.: BP-501397  Purity: ≥95% 4.5  

Tos-PEG4-acid contains a tosyl group and a terminal carboxylic acid. Tosyl group is a very good leaving group for nucleophilic substitution reaction. Terminal carboxylic acid is easy to react with primary and secondary amines and form stable amide bonds in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases the solubility in aqueous media.

Tos-PEG4-acid

Structure of 1453117-42-4

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Molecular Formula
C16H24O8S
Molecular Weight
376.42
Appearance
Pale Yellow or Colorless Oily Matter

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DMSO
Appearance
Pale Yellow or Colorless Oily Matter
Storage
Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
3-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]propanoic acid
Synonyms
3-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]propanoic acid; Tos-PEG4-COOH; 3-(2-(2-(2-(tosyloxy)ethoxy)ethoxy)ethoxy)propanoic acid
Boiling Point
548.3±50.0 °C at 760 mmHg
Density
1.3±0.1 g/cm3
InChI Key
BAXYSSILQKCWFA-UHFFFAOYSA-N
InChI
InChI=1S/C16H24O8S/c1-14-2-4-15(5-3-14)25(19,20)24-13-12-23-11-10-22-9-8-21-7-6-16(17)18/h2-5H,6-13H2,1H3,(H,17,18)
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCOCCC(=O)O

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid | Mal-NH-PEG16-CH2CH2COOPFP ester | Mal-NH-PEG14-CH2CH2COOPFP ester | Boc-HyNic-PEG2-alkyne | mPEG8-amine | N-(PEG1-OH)-N-Boc-PEG2-propargyl | N-PEG3-N'-(azide-PEG3)-Cy5 | 10-(tert-Butoxy)-10-oxodecanoic NHS ester | Hydroxy-PEG10-CH2-Boc | SMCC-Plus | Tos-PEG4-acid

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