Tr-PEG4-OH

 CAS No.: 125274-16-0  Cat No.: BP-501262  Purity: ≥95% 4.5  

Tr-PEG4-OH is a PROTAC linker (belonging to the PEG class) that can be used to synthesize PROTAC molecules. Tr-PEG4-OH is also a non-cleavable 4-unit PEG ADC linker that is used in the synthesis of antibody-conjugated drugs (ADCs).

Tr-PEG4-OH

Structure of 125274-16-0

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Category
PROTAC Linker
Molecular Formula
C27H32O5
Molecular Weight
436.54
Appearance
Light Yellow Oily Matter

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DMSO
Appearance
Light Yellow Oily Matter
Storage
Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
2-[2-[2-(2-trityloxyethoxy)ethoxy]ethoxy]ethanol
Synonyms
Tr-PEG5; Tr-PEG4-alcohol; 2,5,8,11-Tetraoxatridecan-13-ol, 1,1,1-triphenyl-; 3,6,9,12-Tetraoxatridecan-1-ol, 13,13,13-triphenyl-; 11-(Trityloxy)-3,6,9-trioxaundecane-1-ol; 11-Triphenylmethyloxy-3,6,9-trioxaundecan-1-ol; 1,1,1-Triphenyl-2,5,8,11-tetraoxatridecan-13-ol
Boiling Point
559.6±45.0°C at 760 mmHg
Density
1.1±0.1 g/cm3
InChI Key
NVNUQXMSFVIKJG-UHFFFAOYSA-N
InChI
InChI=1S/C27H32O5/c28-16-17-29-18-19-30-20-21-31-22-23-32-27(24-10-4-1-5-11-24,25-12-6-2-7-13-25)26-14-8-3-9-15-26/h1-15,28H,16-23H2
Canonical SMILES
C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OCCOCCOCCOCCO

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It is commonly abbreviated as: C1V1 = C2V2

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Historical Records: Bromo-PEG4-azide | Lipoamido-PEG2-alcohol | Fmoc-N-amido-PEG8-acetic acid | Benzyl-PEG6-amine | THP-PEG8-alcohol | Hydroxy-PEG4-acetic acid | Chloroacetamido-PEG4-NHS ester | Amino-PEG7-amine | Amino-PEG3-C2-sulfonic acid | Amino-PEG9-amine | Tr-PEG4-OH

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