(4R,5S)-nutlin carboxylic acid

 CAS No.: 2306390-08-7  Cat No.: BP-200024 4.5  

(4R,5S)-nutlin carboxylic acid (MDM2 ligand 2) is the Nutlin 3-based MDM2 ligand. (4R,5S)-nutlin carboxylic acid can be connected to the ligand for protein by a linker to form PROTACs.

(4R,5S)-nutlin carboxylic acid

Structure of 2306390-08-7

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Ligand for E3 Ligase
Molecular Formula
C32H32Cl2N4O6
Molecular Weight
639.53

* For research and manufacturing use only. Not for human or clinical use.

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Solubility
10 mM in DMSO
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere
Synonyms
(4R,5S)-nutlin carboxylic acid; MDM2 ligand 2; E3 ligase Ligand 15
Canonical SMILES
O=C1N(CC(O)=O)CCN(C(N2[C@@H](C3=CC=C(Cl)C=C3)[C@@H](C4=CC=C(Cl)C=C4)N=C2C5=CC=C(OC)C=C5OC(C)C)=O)C1

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: SNIPER(TACC3)-1 | ARCC-4 | AT6 | Lenalidomide | AK-1690 | ARD-1676 | PROTAC MDM2 Degrader-3 | PROTAC MDM2 Degrader-4 | Nutlin-C1-amido-PEG4-C2-N3 | PROTAC MDM2 Degrader-1 | (4R,5S)-nutlin carboxylic acid

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