Acid-PEG4-S-S-PEG4-acid

 CAS No.: 2055015-40-0  Cat No.: BP-501142  Purity: ≥95% 4.5  

Acid-PEG4-SS-PEG4-acid is a homobifunctional cleavable linker with carboxylic acid groups at both sides. The terminal carboxylic acids can be reacted with primary amines in the presences of activators such as EDC and HATU to form stable amide bonds. The disulfide bonds can be cleaved by using Dithiothreitol (DTT) reagent.

Acid-PEG4-S-S-PEG4-acid

Structure of 2055015-40-0

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Category
PROTAC Linker
Molecular Formula
C22H42O12S2
Molecular Weight
562.69
Appearance
Pale Yellow Oily Matter

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Appearance
Pale Yellow Oily Matter
Storage
Store at 2-8°C
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
3-[2-[2-[2-[2-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]ethyldisulfanyl]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Synonyms
4,7,10,13,20,23,26,29-octaoxa-16,17-dithiadotriacontanedioic acid; 4,7,10,13,20,23,26,29-Octaoxa-16,17-dithiadotriacontane-1,32-dioic acid
Boiling Point
683.6±55.0°C at 760 mmHg
Density
1.2±0.1 g/cm3
InChI Key
GRXXQSGPDQBZKA-UHFFFAOYSA-N
InChI
InChI=1S/C22H42O12S2/c23-21(24)1-3-27-5-7-29-9-11-31-13-15-33-17-19-35-36-20-18-34-16-14-32-12-10-30-8-6-28-4-2-22(25)26/h1-20H2,(H,23,24)(H,25,26)
Canonical SMILES
C(COCCOCCOCCOCCSSCCOCCOCCOCCOCCC(=O)O)C(=O)O

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: Bis-PEG10-acid | N-(Amino-PEG5)-N-bis(PEG4-acid) | BCN-PEG4-alkyne | TCO-PEG3-acid | SPDP-PEG4-COOH | Boc-Aminooxy-PEG3 | Mal-PEG24-acid | Mal-PEG5-acid | Fmoc-N-Amido-PEG2-alcohol | Propargyl-PEG3-acid | Acid-PEG4-S-S-PEG4-acid

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