AK-1690 - CAS 2984505-88-4

AK-1690 is a potent and selective STAT6 PROTAC degrader. It can be used in the research of STAT6-related human diseases.

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Molecular Formula
C51H56F2N5O11PS
Molecular Weight
1016.05

AK-1690

    • Specification
      • Appearance
        White to off-white solid
        Storage
        Store at 4 °C
        IUPAC Name
        [[2-[[(2S)-1-[(2S,4S)-4-[7-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-4-yl]hept-6-ynoxy]-2-[(2R)-2-phenylmorpholine-4-carbonyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamoyl]-1-benzothiophen-5-yl]-difluoromethyl]phosphonic acid
        Synonyms
        AK 1690; AK1690
    • Properties
      • InChI Key
        BOMRVPKXCINUMI-STKXJIFCSA-N
        InChI
        InChI=1S/C51H56F2N5O11PS/c1-50(2,3)44(55-46(61)42-26-33-25-34(18-20-41(33)71-42)51(52,53)70(65,66)67)49(64)57-28-35(27-39(57)48(63)56-22-24-69-40(30-56)32-14-9-7-10-15-32)68-23-11-6-4-5-8-13-31-16-12-17-36-37(31)29-58(47(36)62)38-19-21-43(59)54-45(38)60/h7,9-10,12,14-18,20,25-26,35,38-40,44H,4-6,11,19,21-24,27-30H2,1-3H3,(H,55,61)(H,54,59,60)(H2,65,66,67)/t35-,38?,39-,40-,44+/m0/s1
        Canonical SMILES
        CC(C)(C)[C@@H](C(=O)N1C[C@H](C[C@H]1C(=O)N2CCO[C@@H](C2)C3=CC=CC=C3)OCCCCCC#CC4=C5CN(C(=O)C5=CC=C4)C6CCC(=O)NC6=O)NC(=O)C7=CC8=C(S7)C=CC(=C8)C(F)(F)P(=O)(O)O
Bio Calculators
Stock concentration: *
Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g
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