COOH-PEG6-COOtBu

 CAS No.: 2093153-84-3  Cat No.: BP-500837  Purity: ≥95% 4.5  

COOH-PEG6-COOtBu is a PEG linker containing a t-butyl-protected carboxyl group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The t-butyl-protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.

COOH-PEG6-COOtBu

Structure of 2093153-84-3

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Category
PROTAC Linker
Molecular Formula
C20H38O10
Molecular Weight
438.51
Appearance
Pale Yellow or Colorless Oily Matter

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DCM, DMF, DMSO, Water
Appearance
Pale Yellow or Colorless Oily Matter
Storage
Store at 2-8°C
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
3-[2-[2-[2-[2-[2-[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Synonyms
Acid-PEG6-t-butyl ester; Acid-PEG6-C2-Boc; HOOCCH2CH2O-PEG5-CH2CH2COOtBu; COOH-PEG6-OtBu; 2,2-Dimethyl-4-oxo-3,7,10,13,16,19,22-heptaoxapentacosan-25-oic acid; 4,7,10,13,16,19-Hexaoxadocosane-1,22-dioic acid, mono(1,1-dimethylethyl) ester
Boiling Point
528.9±50.0°C at 760 mmHg
Density
1.1±0.1 g/cm3
InChI Key
HHEKCKLYBRNNLN-UHFFFAOYSA-N
InChI
InChI=1S/C20H38O10/c1-20(2,3)30-19(23)5-7-25-9-11-27-13-15-29-17-16-28-14-12-26-10-8-24-6-4-18(21)22/h4-17H2,1-3H3,(H,21,22)
Canonical SMILES
CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCC(=O)O

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: DBCO-PEG4-triethoxysilane | COOH-PEG1-COOtBu | Thiol-C10-amide-PEG8 | Ms-PEG3-CH2CH2COOH | Azido-PEG5-propionic acid | Propargyl-PEG2-NHS ester | Propargyl-PEG8-NHS ester | Propargyl-PEG1-COOtBu | Tos-PEG6-THP | DBCO-PEG1-acid | COOH-PEG6-COOtBu

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