Propargyl-PEG1-COOtBu

 CAS No.: 488150-84-1  Cat No.: BP-500569  Purity: ≥95% 4.5  

Propargyl-PEG1-COOtBu is a PEG crosslinker containing a propargyl group and a t-butyl protected carboxyl group. Under the catalysis of copper, propargyl group can react with azide-bearing compounds to produce stable triazole compounds. The hydrophilic PEG spacer increases solubility in aqueous media.

Propargyl-PEG1-COOtBu

Structure of 488150-84-1

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PROTAC Linker
Molecular Formula
C10H16O3
Molecular Weight
184.24
Appearance
Pale Yellow or Colorless Oily Matter

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Appearance
Pale Yellow or Colorless Oily Matter
Storage
Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
tert-butyl 3-prop-2-ynoxypropanoate
Synonyms
Propargyl-PEG1-t-butyl ester; Propargyl-PEG1-Boc; tert-butyl 3-(prop-2-ynyloxy)propanoate; 3-(2-Propyn-1-yloxy)propanoic acid tert-butyl ester
Boiling Point
239.2±15.0 °C at 760 mmHg
Density
1.0±0.1 g/cm3
InChI Key
VDHVLESCKRSEAF-UHFFFAOYSA-N
InChI
InChI=1S/C10H16O3/c1-5-7-12-8-6-9(11)13-10(2,3)4/h1H,6-8H2,2-4H3
Canonical SMILES
CC(C)(C)OC(=O)CCOCC#C

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It is commonly abbreviated as: C1V1 = C2V2

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Historical Records: m-PEG4-Boc | mPEG5-bromide | Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid | DBCO-PEG4-triethoxysilane | COOH-PEG1-COOtBu | Thiol-C10-amide-PEG8 | Ms-PEG3-CH2CH2COOH | Azido-PEG5-propionic acid | Propargyl-PEG2-NHS ester | Propargyl-PEG8-NHS ester | Propargyl-PEG1-COOtBu

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