t-Boc-N-amido-PEG2-bromide

≥95%

Soluble in Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)

Pale Yellow Oily Matter

A cross-linking reagent.

-20°C 3 years powder; -80°C 2 years in solvent

Store at -20°C under inert atmosphere

Room temperature, or blue ice upon request.

tert-butyl N-[2-[2-(2-bromoethoxy)ethoxy]ethyl]carbamate

Br-PEG2-NHBoc; Boc-NH-PEG2-Br; BocNH-PEG2-CH2CH2Br; N-Boc-PEG2-bromide; tert-Butyl (2-(2-(2-bromoethoxy)ethoxy)ethyl)carbamate; 2-[2-(2-t-Boc-aminoethoxy]ethoxy]ethyl Bromide; N-[2-[2-(2-Bromoethoxy)ethoxy]ethyl]carbamic Acid 1,1-Dimethylethyl Ester; 2-[2-[2-(tert-Butoxycarbonylamino)ethoxy]ethoxy]ethyl Bromide; Carbamic acid, N-[2-[2-(2-bromoethoxy)ethoxy]ethyl]-, 1,1-dimethylethyl ester; N-Boc-2-[2-(2-bromoethoxy)ethoxy]ethanamine; 2-Methyl-2-propanyl {2-[2-(2-bromoethoxy)ethoxy]ethyl}carbamate

382.8±27.0°C (Predicted)

1.257±0.06 g/cm3 (Predicted)

WGWDCMKAMHBDPO-UHFFFAOYSA-N

InChI=1S/C11H22BrNO4/c1-11(2,3)17-10(14)13-5-7-16-9-8-15-6-4-12/h4-9H2,1-3H3,(H,13,14)

CC(C)(C)OC(=O)NCCOCCOCCBr

N-Boc-PEG3-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.