Fmoc-N-amido-PEG4-propionic acid

Size	Price	Stock	Quantity
5 g	$376	In stock

Size

Price

Stock

Quantity

5 g

$376

In stock

Purity

≥95%

Solubility

Soluble in DCM, DMF, DMSO

Appearance

Pale Yellow or Colorless Oily Matter

ShelfLife

≥ 2 years

Storage

Store at -20°C, keep in dry and avoid sunlight

Shipping

Room temperature

IUPACName

3-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Synonyms

1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid; Fmoc-N-amido-PEG4-acid; Fmoc-NH-PEG4-CH2CH2COOH; Fmoc-15-Amino-4,7,10,13-tetraoxapentadecacanoic acid; 2,7,10,13,16-Pentaoxa-4-azanonadecan-19-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-; 15-(9-Fluorenylmethyloxycarbonyl)amino-4,7,10,13-tetraoxa-pentadecanoic acid; 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester; 15-(Fmoc-amino)-4,7,10,13-tetraoxapentadecanoic Acid

Boiling Point

682.1±55.0 °C at 760 mmHg

Density

1.219 g/cm3

InChI Key

NUHRPLKTAAVHCZ-UHFFFAOYSA-N

InChI

InChI=1S/C26H33NO8/c28-25(29)9-11-31-13-15-33-17-18-34-16-14-32-12-10-27-26(30)35-19-24-22-7-3-1-5-20(22)21-6-2-4-8-23(21)24/h1-8,24H,9-19H2,(H,27,30)(H,28,29)

Canonical SMILES

C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCC(=O)O

Biological Activity

Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker

ConcentrationVolumeMass	1 mg	5 mg	10 mg
1 mM	2.0511 mL	10.2556 mL	20.5111 mL
5 mM	0.4102 mL	2.0511 mL	4.1022 mL
10 mM	0.2051 mL	1.0256 mL	2.0511 mL

What role does Fmoc-N-amido-PEG4-propionic acid play in DNA?

The headpiece was appended with Fmoc-N-amido-PEG4-propionic acid, which served as a spacer between the DNA and the small-molecule portion of the construct.

8/5/2021

bonding effect

In the experiment, Fmoc N-amino PEG4 propionic acid was a good bonding effect for the small molecular part of the construction.

20/9/2022

Stock concentration: *

Desired final volume: *

Desired concentration: *

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C₁V₁ = C₂V₂