Hydroxy-PEG8-t-butyl ester

 CAS No.: 1334177-84-2  Cat No.: BP-500085  Purity: ≥95% 4.5  

Hydroxy-PEG8-t-butyl ester is a PEG linker containing a hydroxyl group and a t-butyl ester. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl-protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.

Hydroxy-PEG8-t-butyl ester

Structure of 1334177-84-2

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Category
PROTAC Linker
Molecular Formula
C23H46O11
Molecular Weight
498.60
Appearance
Pale Yellow Oily Liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DCM, DMF, DMSO, Water
Appearance
Pale Yellow Oily Liquid
Storage
Store at 2-8°C
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Synonyms
HO-PEG8-CH2CH2COOtBu; Hydroxy-PEG8-(CH2)2-Boc; OH-PEG8-TBA; OH-PEG8-CH2CH2COOtBu; HO-PEG8-t-butyl ester; tert-Butyl 1-Hydroxy-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate; t-Butyl 1-hydroxy-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate; 2-Methyl-2-propanyl 1-hydroxy-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate; 3,6,9,12,15,18,21,24-Octaoxaheptacosan-27-oic acid, 1-hydroxy-, 1,1-dimethylethyl ester; 27-Hydroxy-4,7,10,13,16,19,22,25-octaoxaheptacosanoic acid tert-butyl ester
Boiling Point
549.5±45.0°C at 760 mmHg
Density
1.1±0.1 g/cm3
InChI Key
RBRDLMWBCQQRIQ-UHFFFAOYSA-N
InChI
InChI=1S/C23H46O11/c1-23(2,3)34-22(25)4-6-26-8-10-28-12-14-30-16-18-32-20-21-33-19-17-31-15-13-29-11-9-27-7-5-24/h24H,4-21H2,1-3H3
Canonical SMILES
CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCO
ConcentrationVolumeMass1 mg5 mg10 mg
1 mM2.0056 mL10.0281 mL20.0562 mL
5 mM0.4011 mL2.0056 mL4.0112 mL
10 mM0.2006 mL1.0028 mL2.0056 mL

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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