m-PEG2-Tos

 CAS No.: 50586-80-6  Cat No.: BP-501205  Purity: >98.0% 4.5  

m-PEG2-Tos acts as an intermediate ADC linker with a short PEG2 spacer and tosylate leaving group. It enhances payload solubility and facilitates nucleophilic substitution, supporting reliable conjugation chemistry in antibody-drug conjugate synthesis.

m-PEG2-Tos

Structure of 50586-80-6

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Category
PROTAC Linker
Molecular Formula
C12H18O5S
Molecular Weight
274.33
Appearance
Solid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
>98.0%
Solubility
10 mm in DMSO
Appearance
Solid
ShelfLife
-20°C 3 years powder; -80°C 2 years in solvent
Storage
-20°C
Shipping
Room temperature, or blue ice upon request.
IUPACName
2-(2-methoxyethoxy)ethyl 4-methylbenzenesulfonate
Synonyms
2-(2-Methoxyethoxy)ethyl 4-methylbenzenesulfonate; m-PEG2-Tos; Ethanol, 2-(2-methoxyethoxy)-, 4-methylbenzenesulfonate
InChI Key
PBKGNJXLJQARIN-UHFFFAOYSA-N
InChI
InChI=1S/C12H18O5S/c1-11-3-5-12(6-4-11)18(13,14)17-10-9-16-8-7-15-2/h3-6H,7-10H2,1-2H3
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOC

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Historical Records: Methyltetrazine-amido-PEG7-azide | AcS-PEG4-NH2 | t-Boc-N-amido-PEG4-azide | m-PEG24-Br | N-Mal-N-bis(PEG2-NHS ester) | m-PEG2-Tos

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