Hydroxy-PEG2-t-butyl ester

 CAS No.: 133803-81-3  Cat No.: BP-500078  Purity: ≥95% 4.5  

Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196).

Hydroxy-PEG2-t-butyl ester

Structure of 133803-81-3

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Category
PROTAC Linker
Molecular Formula
C11H22O5
Molecular Weight
234.29
Appearance
Pale Yellow or Colorless Oily Liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DMSO (10 mm)
Appearance
Pale Yellow or Colorless Oily Liquid
Storage
Store at 2-8°C
Shipping
Room temperature
IUPACName
tert-butyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate
Synonyms
HO-PEG2-CH2CH2COOtBu; Hydroxy-PEG2-(CH2)2-Boc; OH-PEG2-TBA; OH-PEG2-CH2CH2COOtBu; HO-PEG2-t-butyl ester; Propanoic acid, 3-[2-(2-hydroxyethoxy)ethoxy]-, 1,1-dimethylethyl ester; t-Butyl 9-hydroxy-4,7-dioxanonanoate; 3-[2-(2-hydroxyethoxy)ethoxy]propionic acid t-butyl ester; 2-Methyl-2-propanyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate
Boiling Point
321.8±22.0 °C at 760 mmHg
Density
1.046±0.1 g/cm3
InChI Key
OKOWESVURLUVMD-UHFFFAOYSA-N
InChI
InChI=1S/C11H22O5/c1-11(2,3)16-10(13)4-6-14-8-9-15-7-5-12/h12H,4-9H2,1-3H3
Canonical SMILES
CC(C)(C)OC(=O)CCOCCOCCO
Biological Activity
Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2- (CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: Pomalidomide-PEG2-C2-NH2 | NH2-PEG2-CH2-Boc | Hydroxy-PEG3-t-butyl ester | Pomalidomide-linker 3 | Fmoc-PEG8-NHS ester | m-PEG2-O-Ph-NH2 | Tos-PEG4-COOtBu | Tos-PEG3-alcohol | Pomalidomide-C4-OH | Pomalidomide-PEG3-CO2H | Hydroxy-PEG2-t-butyl ester

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