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PROTAC AR-V7 degrader-1 - CAS 2767440-24-2

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PROTAC AR-V7 degrader-1 is an orally active selective AR-V7 degrader with a DC50 of 0.32 µM. It functions by recruiting the VHL E3 ligase to the androgen receptor DNA-binding domain (AR DBD). PROTAC AR-V7 degrader-1 is active against the 22Rv1 cell line expressing AR-V7, with an EC50 of 0.88 µM.

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Molecular Formula
C41H52N6O6S2
Molecular Weight
789.02

PROTAC AR-V7 degrader-1

    • Specification
      • Solubility
        DMSO: 110 mg/mL (139.41 mM; Need ultrasonic)
        Appearance
        Solid
        Storage
        Store at -20°C, protect from light
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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