Succinimidyl 2-([4,4'-azipentanamido]ethyl)-1,3'-dithioproprionate - CAS 1253202-38-8

Succinimidyl 2-([4,4'-azipentanamido]ethyl)-1,3'-dithioproprionate unites NHS-amine with diazirine photochemistry, enabling amine-to-any-group crosslinking. Six tunable variants (spacer, cleavable, charge) enhance protein-interaction mapping.

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Molecular Formula
C14H20N4O5S2
Molecular Weight
388.5

Succinimidyl 2-([4,4'-azipentanamido]ethyl)-1,3'-dithioproprionate

    • Specification
      • Appearance
        White to light yellow powder to crystal
        IUPAC Name
        (2,5-dioxopyrrolidin-1-yl) 3-[2-[3-(3-methyldiazirin-3-yl)propanoylamino]ethyldisulfanyl]propanoate
        Synonyms
        SDAD; NHS-SS-Diazirine
    • Properties
      • Density
        1.5±0.1 g/cm3
        InChI Key
        NLPWBELUEANJAT-UHFFFAOYSA-N
        InChI
        InChI=1S/C14H20N4O5S2/c1-14(16-17-14)6-4-10(19)15-7-9-25-24-8-5-13(22)23-18-11(20)2-3-12(18)21/h2-9H2,1H3,(H,15,19)
        Canonical SMILES
        CC1(N=N1)CCC(=O)NCCSSCCC(=O)ON2C(=O)CCC2=O
Bio Calculators
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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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