Structure	Catalog	Product Name	CAS	E3 Ligase	Target	Inquiry
	BPL-201753	6-(5-Cyano-1H-pyrrolo[2,3-b]pyridin-1-yl)-N-(trans-4-((1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-2-oxo-6,9,12-trioxa-3-azatetradecan-14-yl)carbamoyl)cyclohexyl)-4-(isopropylamino)nicotinamide		CRBN	IRAK4	Inquiry
Molecular Weight: 935.01 Molecular Formula: C47H54N10O11 Description: It is a highly selective IRAK4 kinase inhibitor.
	BPL-201754	6-(5-Cyano-1H-pyrrolo[2,3-b]pyridin-1-yl)-N-(trans-4-((1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-2-oxo-6,9,12,15-tetraoxa-3-azaheptadecan-17-yl)carbamoyl)cyclohexyl)-4-(isopropylamino)nicotinamide		CRBN	IRAK4	Inquiry
Molecular Weight: 979.06 Molecular Formula: C49H58N10O12 Description: It is a highly selective IRAK4 kinase inhibitor.
	BPL-201755	2-(2-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)-N-(4'-(2-propylhydrazine-1-carbonyl)-[1,1'-biphenyl]-4-yl)acetamide	2742732-81-4	CRBN	HDAC3	Inquiry
Molecular Weight: 670.72 Molecular Formula: C35H38N6O8 Boiling Point: 923.1±65.0°C at 760 Torr Density: 1.355±0.06 g/cm3 Description: It is a histone deacetylase 3 (HDAC3)-specific PROTAC that potently degrades HDAC3.
	BPL-201756	2-(2-(2-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethoxy)-N-(4'-(2-propylhydrazine-1-carbonyl)-[1,1'-biphenyl]-4-yl)acetamide	2742732-82-5	CRBN	HDAC3	Inquiry
Molecular Weight: 714.78 Molecular Formula: C37H42N6O9 Boiling Point: 944.0±65.0°C at 760 Torr Density: 1.337±0.06 g/cm3 Description: It is a histone deacetylase 3 (HDAC3)-specific PROTAC that potently degrades HDAC3.
	BPL-201757	14-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-N-(4'-(2-propylhydrazine-1-carbonyl)-[1,1'-biphenyl]-4-yl)-3,6,9,12-tetraoxatetradecanamide	2742732-83-6	CRBN	HDAC3	Inquiry
Molecular Weight: 758.83 Molecular Formula: C39H46N6O10 Boiling Point: 962.0±65.0°C at 760 Torr Density: 1.322±0.06 g/cm3 Description: It is a histone deacetylase 3 (HDAC3)-specific PROTAC that potently degrades HDAC3.
	BPL-201758	N1-((S)-1-((2S,4R)-4-Hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-N4-(4'-(2-propylhydrazine-1-carbonyl)-[1,1'-biphenyl]-4-yl)succinamide	2596365-86-3	VHL	HDAC3	Inquiry
Molecular Weight: 796.01 Molecular Formula: C43H53N7O6S Boiling Point: 1035.0±65.0°C at 760 Torr Density: 1.249±0.06 g/cm3 Description: It is a histone deacetylase 3 (HDAC3)-specific PROTAC that potently degrades HDAC3.
	BPL-201759	N1-((S)-1-((2S,4R)-4-Hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-N6-(4'-(2-propylhydrazine-1-carbonyl)-[1,1'-biphenyl]-4-yl)adipamide	2596365-97-6	VHL	HDAC3	Inquiry
Molecular Weight: 824.06 Molecular Formula: C45H57N7O6S Boiling Point: 1046.9±65.0°C at 760 Torr Density: 1.229±0.06 g/cm3 Description: It is a histone deacetylase 3 (HDAC3)-specific PROTAC that potently degrades HDAC3.
	BPL-201760	XZ9002	2596365-98-7	VHL	HDAC3	Inquiry
Molecular Weight: 852.12 Molecular Formula: C47H61N7O6S Boiling Point: 1055.1±65.0°C at 760 Torr Density: 1.211±0.06 g/cm3 Description: XZ9002 is a first-in-class HDAC3-specific PROTAC that potently degrades HDAC3. Importantly, XZ9002 is more effective to inhibit cancer cell proliferation than its proteolysis-inactive counterpart.
	BPL-201761	N1-((S)-1-((2S,4R)-4-Hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-N10-(4'-(2-propylhydrazine-1-carbonyl)-[1,1'-biphenyl]-4-yl)decanediamide	2596366-01-5	VHL	HDAC3	Inquiry
Molecular Weight: 880.17 Molecular Formula: C49H65N7O6S Boiling Point: 1063.9±65.0°C at 760 Torr Density: 1.195±0.06 g/cm3 Description: It is a histone deacetylase 3 (HDAC3)-specific PROTAC that potently degrades HDAC3.
	BPL-201762	4-((6-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-6-oxohexyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione	2229974-86-9	CRBN	CDK4 CDK6	Inquiry
Molecular Weight: 816.92 Molecular Formula: C43H48N10O7 Density: 1.410±0.06 g/cm3 Description: It is a potent and selective CDK4 and CDK6 degrader.
	BPL-201763	4-((2-(2-(2-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-2-oxoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione	2489240-78-8	CRBN	CDK4 CDK6	Inquiry
Molecular Weight: 848.92 Molecular Formula: C43H48N10O9 Melting Point: 92-96°C Density: 1.434±0.06 g/cm3 Description: It is a potent and selective CDK4 and CDK6 degrader.
	BPL-201764	4-((2-(2-(2-(2-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-2-oxoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione	2489240-79-9	CRBN	CDK4 CDK6	Inquiry
Molecular Weight: 892.97 Molecular Formula: C45H52N10O10 Melting Point: 140-144°C Density: 1.414±0.06 g/cm3 Description: It is a potent and selective CDK4 and CDK6 degrader.
	BPL-201765	4-((2-(2-(2-((5-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-5-oxopentyl)oxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione	2489240-80-2	CRBN	CDK4 CDK6	Inquiry
Molecular Weight: 935.05 Molecular Formula: C48H58N10O10 Melting Point: 112-114°C Density: 1.373±0.06 g/cm3 Description: It is a potent and selective CDK4 and CDK6 degrader.
	BPL-201766	4-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-N-(3-(4-(3-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)propoxy)butoxy)propyl)-4-oxobutanamide	2489240-82-4	CRBN	CDK4 CDK6	Inquiry
Molecular Weight: 990.13 Molecular Formula: C51H63N11O10 Melting Point: 176-180°C Density: 1.356±0.06 g/cm3 Description: It is a potent and selective CDK4 and CDK6 degrader.
	BPL-201767	4-((6-((5-((5-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-5-oxopentyl)oxy)pentyl)oxy)hexyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione	2489240-83-5	CRBN	CDK4 CDK6	Inquiry
Molecular Weight: 989.19 Molecular Formula: C53H68N10O9 Melting Point: 110-112°C Density: 1.306±0.06 g/cm3 Description: It is a potent and selective CDK4 and CDK6 degrader.
	BPL-201768	4-((6-((6-((6-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-6-oxohexyl)oxy)hexyl)oxy)hexyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione	2489240-84-6	CRBN	CDK4 CDK6	Inquiry
Molecular Weight: 1017.24 Molecular Formula: C55H72N10O9 Melting Point: 110-112°C Density: 1.287±0.06 g/cm3 Description: It is a potent and selective CDK4 and CDK6 degrader.
	BPL-201769	4-((4-(4-(4-((6-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-6-oxohexyl)oxy)butoxy)butoxy)butyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione	2489240-85-7	CRBN	CDK4 CDK6	Inquiry
Molecular Weight: 1033.24 Molecular Formula: C55H72N10O10 Melting Point: 96-100°C Density: 1.297±0.06 g/cm3 Description: It is a potent and selective CDK4 and CDK6 degrader.
	BPL-201770	4-((28-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-28-oxo-7,12,17,22-tetraoxaoctacosyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione	2489240-86-8	CRBN	CDK4 CDK6	Inquiry
Molecular Weight: 1133.40 Molecular Formula: C61H84N10O11 Melting Point: 68-72°C Density: 1.256±0.06 g/cm3 Description: It is a potent and selective CDK4 and CDK6 degrader.
	BPL-201771	4-((28-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-28-oxo-7,10,13,16,19,22-hexaoxaoctacosyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione	2489240-87-9	CRBN	CDK4 CDK6	Inquiry
Molecular Weight: 1137.35 Molecular Formula: C59H80N10O13 Melting Point: 80-82°C Density: 1.290±0.06 g/cm3 Description: It is a potent and selective CDK4 and CDK6 degrader.
	BPL-201772	(2S,4R)-1-((S)-2-(8-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)octanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2229975-01-1	VHL	CDK4 CDK6	Inquiry
Molecular Weight: 1002.29 Molecular Formula: C54H71N11O6S Melting Point: 96-98°C Density: 1.269±0.06 g/cm3 Description: It is a potent and selective CDK4 and CDK6 degrader.

PROTAC Library